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Penetration of cefuroxime into the cerebrospinal fluid of patients with traumatic brain injury

Kossmann, T. ; Hans, V. ; Stocker, R. ; Imhof, H.-G ; Joos, B. ; Trentz, O. ; Morganti-Kossmann, M. C.

In: Journal of Antimicrobial Chemotherapy, 1996, vol. 37, no. 1, p. 161-167

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    Titre
    • Penetration of cefuroxime into the cerebrospinal fluid of patients with traumatic brain injury
    Auteur
    • Kossmann, T.. Department of Surgery, Division of Trauma Surgery, Division of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    • Hans, V.. Department of Surgery, Division of Trauma Surgery, Division of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    • Stocker, R.. Department of Surgery, Division of Trauma Surgery, Division of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    • Imhof, H.-G. Department of NeurosurgeryDivision of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    • Joos, B.. Department of Internal Medicine, Division of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    • Trentz, O.. Department of Surgery, Division of Trauma Surgery, Division of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    • Morganti-Kossmann, M. C.. Department of Surgery, Division of Trauma Surgery, Division of Infectious Diseased, University of Zürich, Medical School CH-8091 Zürich, Switzerland
    Type de document
    • Postprint
    Langue
    • Inglese
    Publié dans
    • Journal of Antimicrobial Chemotherapy, 1996, vol. 37, no. 1, p. 161-167. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:292773
    Summary
    Cefuroxime levels were measured in cerebrospinal fluid (CSF) and serum of four patients with traumatic brain injury following the implantation of intraventricular catheters. The levels ranged from 0.15 to 2.03 μg/mL in CSF and from 1.8 to 66.9 μg/mL in serum. No ventriculostomy related infections were detected