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Long-distance charge transport through DNA. An extended hopping model

Giese, Bernd ; Spichty, Martin ; Wessely, Stefan

In: Pure and Applied Chemistry, 2001, vol. 73, no. 3, p. 449-453

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    Title
    • Long-distance charge transport through DNA. An extended hopping model
    Author
    • Giese, Bernd. Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland
    • Spichty, Martin. Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland
    • Wessely, Stefan. Department of Chemistry, University of Basel, St. Johanns Ring 19, CH-4056 Basel, Switzerland
    Document Type
    • Postprint
    Classification
    • Health
    OAI-PMH Identifier
    • oai:doc.rero.ch:291945
    Summary
    Long-distance transfer of a positive charge through DNA can be described by a hopping model. In double strands where the (A:T)n bridges between the guanines are short (n 3), the charge hops only between guanines, and each hopping step depends strongly upon the guanine to guanine distances. In strands where the (A:T)n sequences between the guanines are rather long (n 4), also the adenines act as charge carriers. To predict the yields of the H2O-trapping products one has to take into account not only the charge-transfer rates but also the rates of H2O-trapping reactions