Fulltext

The case for strategic international alliances to harness nutritional genomics for public and personal health

Kaput, Jim ; Ordovas, Jose M. ; Ferguson, Lynnette ; van Ommen, Ben ; Rodriguez, Raymond L. ; Allen, Lindsay ; Ames, Bruce N. ; Dawson, Kevin ; German, Bruce ; Krauss, Ronald ; Malyj, Wasyl ; Archer, Michael C. ; Barnes, Stephen ; Bartholomew, Amelia ; Birk, Ruth ; van Bladeren, Peter ; Bradford, Kent J. ; Brown, Kenneth H. ; Caetano, Rosane ; Castle, David ; Chadwick, Ruth ; Clarke, Stephen ; Clément, Karine ; Cooney, Craig A. ; Corella, Dolores ; da Cruz, Ivana Beatrice Manica ; Daniel, Hannelore ; Duster, Troy ; Ebbesson, Sven O. E. ; Elliott, Ruan ; Fairweather-Tait, Susan ; Felton, Jim ; Fenech, Michael ; Finley, John W. ; Fogg-Johnson, Nancy ; Gill-Garrison, Rosalynn ; Gibney, Michael J. ; Gillies, Peter J. ; Gustafsson, Jan-Ake ; Hartman, John L. ; He, Lin ; Hwang, Jae-Kwan ; Jais, Jean-Philippe ; Jang, Yangsoo ; Joost, Hans ; Junien, Claudine ; Kanter, Mitchell ; Kibbe, Warren A. ; Koletzko, Berthold ; Korf, Bruce R. ; Kornman, Kenneth ; Krempin, David W. ; Langin, Dominique ; Lauren, Denis R. ; Lee, Jong Ho ; Leveille, Gilbert A. ; Lin, Su-Ju ; Mathers, John ; Mayne, Michael ; McNabb, Warren ; Milner, John A. ; Morgan, Peter ; Muller, Michael ; Nikolsky, Yuri ; van der Ouderaa, Frans ; Park, Taesun ; Pensel, Norma ; Perez-Jimenez, Francisco ; Poutanen, Kaisa ; Roberts, Matthew ; Saris, Wim H.M. ; Schuster, Gertrud ; Shelling, Andrew N. ; Simopoulos, Artemis P. ; Southon, Sue ; Tai, E. Shyong ; Towne, Bradford ; Trayhurn, Paul ; Uauy, Ricardo ; Visek, Willard J. ; Warden, Craig ; Weiss, Rick ; Wiencke, John ; Winkler, Jack ; Wolff, George L. ; Zhao-Wilson, Xi ; Zucker, Jean-Daniel

In: British Journal of Nutrition, 2005, vol. 94, no. 5, p. 623-632

Add to personal list
    Title
    • The case for strategic international alliances to harness nutritional genomics for public and personal health
    Author
    • Kaput, Jim. Center of Excellence in Nutritional Genomics, University of California, Davis, CA 95616, USA
    • Ordovas, Jose M.. Nutrition and Genomics Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    • Ferguson, Lynnette. National Centre for Research Excellence in Nutrigenomics, University of Auckland, Auckland, New Zealand
    • van Ommen, Ben. NuGO - TNO Quality of Life, Zeist, The Netherlands
    • Rodriguez, Raymond L.. Center of Excellence in Nutritional Genomics, University of California, Davis, CA 95616, USA
    • Allen, Lindsay. USDA-ARS Western Human Nutrition Research Center at the University of California, Davis, CA 95616, USA
    • Ames, Bruce N.. Children's Hospital of Oakland Research Institute, Oakland, CA 94609, USA
    • Dawson, Kevin. Center of Excellence in Nutritional Genomics, University of California, Davis, CA 95616, USA
    • German, Bruce. Department of Food Science and Technology, University of California, Davis, CA 95616, USA
    • Krauss, Ronald. Children's Hospital of Oakland Research Institute, Oakland, CA 94609, USA
    • Malyj, Wasyl. Center of Excellence in Nutritional Genomics, University of California, Davis, CA 95616, USA
    • Archer, Michael C.. University of Alabama Center for Nutrient-Gene Interactions, University of Alabama, Birmingham, Alabama 35294-0005, USA
    • Barnes, Stephen. Laboratory of Nutrigenomic Medicine, Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    • Bartholomew, Amelia. Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada
    • Birk, Ruth. Department of Biotechnology Engineering, Ben-Gurion University at the Negev, Beer-Sheeva 84105, Israel
    • van Bladeren, Peter. Nestlé Research Center, Lausanne, Switzerland
    • Bradford, Kent J.. Seed Biotechnology Center, Plant Reproductive Biology, University of California, Davis, CA 95616, USA
    • Brown, Kenneth H.. Program in International Nutrition, Department of Nutrition University of California, Davis, CA 95616, USA
    • Caetano, Rosane. Department of Health Sciences, Universidade Regional do Noroeste do Estado do Rio Grande do Sul, Rua São Francisco, 501 - Bairro São Geraldo Ijuí - RS - Brasil
    • Castle, David. Department of Philosophy, University of Guelph, Ontario, Canada
    • Chadwick, Ruth. ESRC Centre for the Economic and Social Aspects of Genomics (CESAGen), Lancaster University, Lancaster LA1 4YG, UK
    • Clarke, Stephen. McNeil Nutritionals, New Brunswick, NJ, USA
    • Clément, Karine. INSERM ‘Avenir' Nutrition dpt Hôtel-Dieu, EA3502, UMPC Paris 6, France
    • Cooney, Craig A.. Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    • Corella, Dolores. Genetic and Molecular Epidemiology Unit, School of Medicine, University of Valencia, Valencia, Spain
    • da Cruz, Ivana Beatrice Manica. Department of Health Sciences, Universidade Regional do Noroeste do Estado do Rio Grande do Sul, Rua São Francisco, 501 - Bairro São Geraldo Ijuí - RS - Brasil
    • Daniel, Hannelore. NuGO - Molecular Nutrition Unit, Technical University of Munich, Hochfeldweg 2, 85350 Freising-Weihenstephan, Germany
    • Duster, Troy. Department of Sociology, New York University, NY, NY 10003 and Institute for the Study of Social Change, University of California, Berkeley, CA 94720-5670, USA
    • Ebbesson, Sven O. E.. Department of Neurological Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    • Elliott, Ruan. Institute of Food Research, Norwich NR4 7UA, UK
    • Fairweather-Tait, Susan. Institute of Food Research, Norwich NR4 7UA, UK
    • Felton, Jim. Biology and Biotechnology Research Program, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA
    • Fenech, Michael. CSIRO Health Sciences and Nutrition, Adelaide SA, 5000, Australia
    • Finley, John W.. AM Todd, Montgomeryville, PA 18936, USA
    • Fogg-Johnson, Nancy. Life Science Alliance, Villanova, PA 19085, USA
    • Gill-Garrison, Rosalynn. Sciona, Inc., Boulder, CO 80302, USA
    • Gibney, Michael J.. NuGO - Nutrition Unit Department of Clinical Medicine, Trinity College, Dublin, Republic of Ireland
    • Gillies, Peter J.. Human Health Sciences, DuPont Nutrition & Health, Newark, DE, Centre of Excellence in Nutrigenomics, Penn State University, University Park, PA, USA
    • Gustafsson, Jan-Ake. Department of Medical Nutrition, Center for Biotechnology, Karolinska Instututet, Novum, SE-141 86, Huddinge, Sweden
    • Hartman, John L.. Department of Genetics, University of Alabama, Birmingham, Alabama 35294-0024, USA
    • He, Lin. Institute for Nutritional Sciences, SIBS, Chinese Academy of Sciences, Shanghai 200031, China
    • Hwang, Jae-Kwan. Department of Biotechnology, Yonsei University, Seoul, Korea
    • Jais, Jean-Philippe. Department of Biostatistics and Bioinformatics, Hôpital Necker Enfants Malades, Université Paris 5, Paris, France
    • Jang, Yangsoo. Department of Internal Medicine, Yonsei University, Seoul, Korea
    • Joost, Hans. NuGO - German Institute for Human Nutrition, Potsdam Rehbrücke, Germany
    • Junien, Claudine. Department of Genetics, Hôpital Necker Enfants Malades, Clinique Maurice Larny, Paris, 75743, France
    • Kanter, Mitchell. Cargill, Inc., Wayzata, MN 55305, USA
    • Kibbe, Warren A.. Center of Genetic Medicine, Center for Functional Genomics, Robert Lurie Comprehensive Cancer Center, NorthWestern University Medical School, Chicago, IL 60611, USA
    • Koletzko, Berthold. Dr von Hauner Children's Hospital, University of Munich, Germany
    • Korf, Bruce R.. Department of Genetics, University of Alabama, Birmingham, Alabama 35294-0024, USA
    • Kornman, Kenneth. Interleukin Genetics, Inc., Waltham, MA 02452, USA
    • Krempin, David W.. Nutrilite Division of Access Business Group, LLC, Buena Park, CA 90622, USA
    • Langin, Dominique. Obesity Research Unit, Institut Louis Bugnard, French Institute of Health and Medical Research (Inserm), Toulouse University Hospitals, Paul Sabatier University, 31059 Toulouse, France
    • Lauren, Denis R.. National Centre for Research Excellence in Nutrigenomics, University of Auckland, Auckland, New Zealand
    • Lee, Jong Ho. Department of Food and Nutrition, Yonsei University, Seoul, Korea
    • Leveille, Gilbert A.. Food Systems Design, Denville, NJ 07834, USA
    • Lin, Su-Ju. Department of Microbiology, Division of Biological Sciences, University of California, Davis, CA 95616, USA
    • Mathers, John. NuGO - Human Nutrition Research Centre, Newcastle University, UK
    • Mayne, Michael. Institute for Nutrisciences and Health, National Research Council of Canada, Charlottetown, Prince Edward Island, Canada C1A 5T1
    • McNabb, Warren. National Centre for Research Excellence in Nutrigenomics, University of Auckland, Auckland, New Zealand
    • Milner, John A.. Nutritional Science Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    • Morgan, Peter. Rowett Research, Greenburn Road, Bucksburn, Aberdeen AB21 9SB, Scotland, UK
    • Muller, Michael. NuGO - Dutch Innovative Cluster Nutrigenomics, Wageningen Centre for Food Science and Nutrition, Metabolism and Genomics, Wageningen University, Wageningen, The Netherlands
    • Nikolsky, Yuri. GeneGo, Inc., St Joseph, MI 49085, USA
    • van der Ouderaa, Frans. Unilever Corporate Research, Colworth House, Sharnbrook, Beds MK44 1PY, UK
    • Park, Taesun. Department of Food and Nutrition, Yonsei University, Seoul, Korea
    • Pensel, Norma. Instituto Tecnología de Alimentos, Instituto Nacional de Tecnología Agropecuaria (INTA), Buenos Aires, Argentina
    • Perez-Jimenez, Francisco. Hospital Universitario Reina Sofia, Unidad Lipidos & Arteriosclerosis, Cordoba, Spain
    • Poutanen, Kaisa. Food and Health Research Centre, University of Kuopio, Mediteknia, Box 1627, 70211 KUOPIO, Finland
    • Roberts, Matthew. Purina/Nestle, St Louis, MO, USA
    • Saris, Wim H.M.. NuGO - Nutrition and Toxicology Research Institute NUTRIM, University of Maastricht, The Netherlands
    • Schuster, Gertrud. Department of Nutrition, University of California, Davis, CA 95616-8669, USA
    • Shelling, Andrew N.. National Centre for Research Excellence in Nutrigenomics, University of Auckland, Auckland, New Zealand
    • Simopoulos, Artemis P.. The Center for Genetics, Nutrition and Health, Washington, DC 20009, USA
    • Southon, Sue. NuGO - Institute of Food Research, Norwich NR4 7UA, UK
    • Tai, E. Shyong. Department of Endocrinology, Singapore General Hospital, Singapore 169608, Republic of Singapore
    • Towne, Bradford. Department of Community Health, Wright State University School of Medicine, Dayton, OH 45401-0927, USA
    • Trayhurn, Paul. Obesity Biology Unit, Liverpool Centre for Nutritional Genomics, School of Clinical Sciences, University of Liverpool, Liverpool L69 3GA, UK
    • Uauy, Ricardo. Public Health Nutrition, London School of Hygiene and Tropical Medicine, London, and Instituto de Nutricion y Tecnologia de los Alimentos (INTA), University of Chile, Santiago, Chile
    • Visek, Willard J.. Department of Internal Medicine, University of Illinois College of Medicine, Urbana, IL 61821, USA
    • Warden, Craig. Neurobiology, Physiology, and Behavior Section of Division of Biological Sciences, University of California, Davis, CA 95616, USA
    • Weiss, Rick. Viocare Technologies, Inc., Princeton, NJ 08542, USA
    • Wiencke, John. Department of Epidemiology and Biostatistics and Division of Neuroepidemiology, University of California, San Francisco, CA 94143-0112, USA
    • Winkler, Jack. Food and Health Research, London N1 7AB, UK
    • Wolff, George L.. National Center for Toxicological Research/FDA, Jefferson, AR 72079, USA
    • Zhao-Wilson, Xi. BioMarker Pharmaceuticals, Inc., Campbell, CA 95008, USA
    • Zucker, Jean-Daniel. LIM&BIO, EPML-CNRS IAPuces, Universite Paris XIII, 74 rue Marcel Cachin 93017 Bobigny Cedex, France
    Document Type
    • Postprint
    Language
    • English
    Published in
    • British Journal of Nutrition, 2005, vol. 94, no. 5, p. 623-632. Cambridge University Press
    Other Version
    OAI-PMH Identifier
    • oai:doc.rero.ch:291828
    Summary
    Nutrigenomics is the study of how constituents of the diet interact with genes, and their products, to alter phenotype and, conversely, how genes and their products metabolise these constituents into nutrients, antinutrients, and bioactive compounds. Results from molecular and genetic epidemiological studies indicate that dietary unbalance can alter gene-nutrient interactions in ways that increase the risk of developing chronic disease. The interplay of human genetic variation and environmental factors will make identifying causative genes and nutrients a formidable, but not intractable, challenge. We provide specific recommendations for how to best meet this challenge and discuss the need for new methodologies and the use of comprehensive analyses of nutrient-genotype interactions involving large and diverse populations. The objective of the present paper is to stimulate discourse and collaboration among nutrigenomic researchers and stakeholders, a process that will lead to an increase in global health and wellness by reducing health disparities in developed and developing countries