Fulltext

neXtProt: a knowledge platform for human proteins

Lane, Lydie ; Argoud-Puy, Ghislaine ; Britan, Aurore ; Cusin, Isabelle ; Duek, Paula D. ; Evalet, Olivier ; Gateau, Alain ; Gaudet, Pascale ; Gleizes, Anne ; Masselot, Alexandre ; Zwahlen, Catherine ; Bairoch, Amos

In: Nucleic Acids Research, 2012, vol. 40, no. D1, p. D76-D83

Add to personal list
    Title
    • neXtProt: a knowledge platform for human proteins
    Author
    • Lane, Lydie. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Argoud-Puy, Ghislaine. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Britan, Aurore. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Cusin, Isabelle. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Duek, Paula D.. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Evalet, Olivier. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Gateau, Alain. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Gaudet, Pascale. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Gleizes, Anne. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Masselot, Alexandre. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Zwahlen, Catherine. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    • Bairoch, Amos. CALIPHO group, Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland, Department of Human Protein Sciences, Faculty of Medicine, University of Geneva and GeneBio, c/o Swiss Institute of Bioinformatics, CMU - 1, rue Michel Servet 1211 Geneva 4, Switzerland
    Document Type
    • Postprint
    Language
    • English
    Published in
    • Nucleic Acids Research, 2012, vol. 40, no. D1, p. D76-D83. Oxford University Press
    Other Version
    Classification
    • Health
    Keywords
    OAI-PMH Identifier
    • oai:doc.rero.ch:291301
    Summary
    neXtProt (http://www.nextprot.org/) is a new human protein-centric knowledge platform. Developed at the Swiss Institute of Bioinformatics (SIB), it aims to help researchers answer questions relevant to human proteins. To achieve this goal, neXtProt is built on a corpus containing both curated knowledge originating from the UniProtKB/Swiss-Prot knowledgebase and carefully selected and filtered high-throughput data pertinent to human proteins. This article presents an overview of the database and the data integration process. We also lay out the key future directions of neXtProt that we consider the necessary steps to make neXtProt the one-stop-shop for all research projects focusing on human proteins