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Pathogenesis, diagnosis and treatment of Rasmussen encephalitis : A European consensus statement

Bien, C. G. ; Granata, T. ; Antozzi, C. ; Cross, J. H. ; Dulac, O. ; Kurthen, M. ; Lassmann, H. ; Mantegazza, R. ; Villemure, J.-G ; Spreafico, R. ; Elger, C. E.

In: Brain, 2005, vol. 128, no. 3, p. 454-471

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    Titre
    • Pathogenesis, diagnosis and treatment of Rasmussen encephalitis
      A European consensus statement
    Auteur
    • Bien, C. G.. University of Bonn, Department of Epileptology, Bonn, Germany
    • Granata, T.. Instituto Nazionale Neurologico ‘C. Besta', Milan, Italy
    • Antozzi, C.. Instituto Nazionale Neurologico ‘C. Besta', Milan, Italy
    • Cross, J. H.. Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, London, UK
    • Dulac, O.. Service de Maladies Métaboliques et Neurologie Hôpital Necker Enfant Malades, Paris, France
    • Kurthen, M.. University of Bonn, Department of Epileptology, Bonn, Germany
    • Lassmann, H.. Medical University of Vienna, Brain Research Institute, Vienna, Austria, and
    • Mantegazza, R.. Instituto Nazionale Neurologico ‘C. Besta', Milan, Italy
    • Villemure, J.-G. Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    • Spreafico, R.. Instituto Nazionale Neurologico ‘C. Besta', Milan, Italy
    • Elger, C. E.. University of Bonn, Department of Epileptology, Bonn, Germany
    Type de document
    • Postprint
    Langue
    • Anglais
    Publié dans
    • Brain, 2005, vol. 128, no. 3, p. 454-471. Oxford University Press
    Autre version électronique
    Identifiant OAI-PMH
    • oai:doc.rero.ch:290116
    Summary
    Rasmussen encephalitis (RE) is a rare but severe immune-mediated brain disorder leading to unilateral hemispheric atrophy, associated progressive neurological dysfunction and intractable seizures. Recent data on the pathogenesis of the disease, its clinical and paraclinical presentation, and therapeutic approaches are summarized. Based on these data, we propose formal diagnostic criteria and a therapeutic pathway for the management of RE patients