Infrequent Replication of Parvovirus B19 and Erythrovirus Genotypes 2 and 3 among HIV-Infected Patients with Chronic Anemia
Ferry, Tristan ; Hirschel, Bernard ; Dang, Thanh ; Meylan, Pascal ; Delhumeau, Cécile ; Rauch, Andri ; Weber, Rainer ; Elzi, Luigia ; Bernasconi, Enos ; Schmid, Patrick ; Calmy, Alexandra
In: Clinical Infectious Diseases, 2010, vol. 50, no. 1, p. 115-118
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- We investigated the role that erythroviruses (parvovirus B19 and erythrovirus genotypes 2 and 3) play in the lives of immunosuppressed HIV-infected patients with chronic anemia. We screened the serum samples of 428 patients by specific ultrasensitive real-time polymerase chain reaction assay. Sixteen patients had circulating DNA, with no apparent clinical impact. Erythrovirus-associated anemia is an extremely rare event in HIV-infected patients