Université de Fribourg

A biological perspective toward the interaction of theranostic nanoparticles with the bloodstream – what needs to be considered?

Clift, Martin J. D. ; Dechézelles, Jean-François ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: Chemical Engineering, 2015, vol. 3, p. 7

Nanomedicine intends to create and further use novel materials at the nanoscale in order to provide an improvement upon current medical applications for human healthcare (ESF, 2005; Etheridge et al., 2013). In line with the advances made within nanotechnology since the late twentieth century (Mamalis, 2007) nanomedicine has received heightened attention due to its potential advantages, most...

Université de Fribourg

Magnetic microreactors for efficient and reliable magnetic nanoparticle surface functionalization

Digigow, Reinaldo G. ; Dechézelles, Jean-François ; Kaufmann, J. ; Vanhecke, Dimitri ; Knapp, H. ; Lattuada, Marco ; Rothen-Rutishauser, Barbara ; Petri-Fink, Alke

In: Lab on a Chip, 2014, p. -

Microreactors have attracted wide attention in the nano- and biotechnology fields because they offer many advantages over standard liquid phase reactions. We report the development of a magnetic microreactor for reliable, fast and efficient surface functionalization of superparamagnetic iron oxide nanoparticles (SPIONs). A comprehensive study of the development process in terms of setup, loading...