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A 340 kDa hyaluronic acid secreted by human vascular smooth muscle cells regulates their proliferation and migration

Papakonstantinou, E. ; Karakiulakis, G. ; Eickelberg, O. ; Perruchoud, A.P. ; Block, L.-H ; Roth, M.

In: Glycobiology, 1998, vol. 8, no. 8, p. 821-830

P-2: Human vascular smooth muscle cell DNA synthesis stimulated by native low density lipoproteins involves redox-sensitive pathways. Inhibition by N-acetylcysteine and green tea constituents

Locher, Rudolf ; Zhang, Jian ; Suter, Paolo M. ; Vetter, Wilhelm ; Barton, Matthias

In: American Journal of Hypertension, 2001, vol. 14, no. S1, p. 29A-29A

Imbalance of Endothelium-derived Relaxing and Contracting Factors : A New Concept in Hypertension?

Lüscher, T. F.

In: American Journal of Hypertension, 1990, vol. 3, no. 4, p. 317-330

Different vascular smooth muscle cell apoptosis in the human internal mammary artery and the saphenous vein: implications for bypass graft disease

Frischknecht, Karin ; Greutert, Helen ; Weisshaupt, Christian ; Kaspar, Mathias ; Yang, Zhihong ; Lüscher, Thomas F. ; Carrel, Thierry P. ; Tanner, Felix C.

In: Journal of Vascular Research, 2006, vol. 43, no. 4, p. 338-346

The remarkable patency of internal mammary artery (MA) grafts compared to saphenous vein (SV) grafts has been related to different biological properties of the two blood vessels. We examined whether proliferation and apoptosis of vascular smooth muscle cells (VSMC) from human coronary artery bypass vessels differ according to patency rates. Methods and Results: Proliferation rates to serum...

Thrombin Stimulates Human Endothelial Arginase Enzymatic Activity via RhoA/ROCK Pathway

Ming, Xiu-Fen ; Barandier, Christine ; Viswambharan, Hema ; Kwak, Brenda R. ; Mach, François ; Mazzolai, Lucia ; Hayoz, Daniel ; Ruffieux, Jean ; Rusconi, Sandro ; Montani, Jean-Pierre ; Yang, Zhihong

In: Circulation, 2004, vol. 110, p. 3708-3714

Background— Arginase competes with endothelial nitric oxide synthase (eNOS) for the substrate L-arginine and decreases NO production. This study investigated regulatory mechanisms of arginase activity in endothelial cells and its role in atherosclerosis. Methods and Results— In human endothelial cells isolated from umbilical veins, thrombin concentration- and time-dependently stimulated...