In: European Heart Journal, 2010, vol. 31, no. 2, p. 236-242
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In: European Heart Journal, 2014, vol. 35, no. 12, p. 808-820
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In: Cardiovascular Research, 2017, vol. 113, no. 1, p. 61–69
The P2Y12 antagonist ticagrelor reduces mortality in patients with acute coronary syndrome (ACS), compared with clopidogrel, and the mechanisms underlying this effect are not clearly understood. Arterial thrombosis is the key event in ACS; however, direct vascular effects of either ticagrelor or clopidogrel with focus on arterial thrombosis and its key trigger tissue factor have not been...
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Thèse de doctorat : Université de Fribourg, 2006 ; no. 1543.
The innermost layer of a vessel, the endothelium, forms an interface between the circulating blood in the vascular lumen and the vessel wall. The endothelium functions as a.) a physical barrier between the blood and the vessel; b.) a vital source of enzymes activating and deactivating cardiovascular hormones; c.) a site of production of relaxing and contracting factors; and d.) a source of growth...
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In: Circulation, 2006, vol. 114, no. 14, p. 1512-1521
Background— Subacute stent thrombosis is a major clinical concern, and the search for new molecules to cover stents remains important. Dimethyl sulfoxide (DMSO) is used for preservation of hematopoietic progenitor cells and is infused into patients undergoing bone marrow transplantation. Despite its intravenous application, the impact of DMSO on vascular cells has not been assessed....
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