Université de Fribourg

A conserved RxLR effector interacts with host RABA-type GTPases to inhibit vesicle-mediated secretion of antimicrobial proteins

Tomczynska, Iga ; Stumpe, Michael ; Mauch, Felix

In: The Plant Journal, 2018, vol. 95, no. 2, p. 187–203

Plant pathogens of the oomycete genus Phytophthora produce virulence factors, known as RxLR effector proteins that are transferred into host cells to suppress disease resistance. Here, we analyse the function of the highly conserved RxLR24 effector of Phytophthora brassicae. RxLR24 was expressed early in the interaction with Arabidopsis plants and ectopic expression in the host enhanced leaf...

Université de Fribourg

Protein phosphatase AP2C1 negatively regulates basal resistance and defense responses to Pseudomonas syringae

Shubchynskyy, Volodymyr ; Boniecka, Justyna ; Schweighofer, Alois ; Simulis, Justinas ; Kvederaviciute, Kotryna ; Stumpe, Michael ; Mauch, Felix ; Balazadeh, Salma ; Mueller-Roeber, Bernd ; Boutrot, Freddy ; Zipfel, Cyril ; Meskiene, Irute

In: Journal of Experimental Botany, 2017, p. -

Mitogen-activated protein kinases (MAPKs) mediate plant immune responses to pathogenic bacteria. However, less is known about the cell autonomous negative regulatory mechanism controlling basal plant immunity. We report the biological role of Arabidopsis thaliana MAPK phosphatase AP2C1 as a negative regulator of plant basal resistance and defense responses to Pseudomonas syringae. AP2C2, a...

Université de Neuchâtel

Expression Profile Matrix of Arabidopsis Transcription Factor Genes Suggests Their Putative Functions in Response to Environmental Stresses

Chen, Wenqiong ; Provart, Nicholas J. ; Glazebrook, Jane ; Katagiri, Fumiaki ; Chang, Hur-Song ; Eulgem, Thomas ; Mauch, Felix ; Luan, Sheng ; Zou, Guangzhou ; Whitham, Steve A. ; Budworth, Paul R. ; Tao, Yi ; Xie, Zhiyi ; Chen, Xi ; Lam, Steve ; Kreps, Joel A. ; Harper, Jeffery F. ; Si-Ammour, Azeddine ; Mauch-Mani, Brigitte ; Heinlein, Manfred ; Kobayashi, Kappei ; Hohn, Thomas ; Dangl, Jeffery L. ; Wang, Xun ; Zhu, Tong

In: The Plant Cell, 2002, vol. 14, no. 3, p. 559-574

Numerous studies have shown that transcription factors are important in regulating plant responses to environmental stress. However, specific functions for most of the genes encoding transcription factors are unclear. In this study, we used mRNA profiles generated from microarray experiments to deduce the functions of genes encoding known and putative Arabidopsis transcription factors. The mRNA...

Université de Fribourg

The PP2C-type phosphatase AP2C1, which negatively regulates MPK4 and MPK6, modulates innate immunity, jasmonic acid, and ethylene levels in Arabidopsis

Schweighofer, Alois ; Kazanaviciute, Vaiva ; Scheikl, Elisabeth ; Teige, Markus ; Doczi, Robert ; Hirt, Heribert ; Schwanninger, Manfred ; Kant, Merijn ; Schuurink, Robert ; Mauch, Felix ; Buchala, Antony ; Cardinale, Francesca ; Meskiene, Irute

In: The Plant Cell, 2007, vol. 19, no. 7, p. 2213-2224

Wound signaling pathways in plants are mediated by mitogen-activated protein kinases (MAPKs) and stress hormones, such as ethylene and jasmonates. In Arabidopsis thaliana, the transmission of wound signals by MAPKs has been the subject of detailed investigations; however, the involvement of specific phosphatases in wound signaling is not known. Here, we show that AP2C1, an...