Université de Fribourg

Flavonol-induced changes in PIN2 polarity and auxin transport in the Arabidopsis thaliana rol1-2 mutant require phosphatase activity

Kuhn, Benjamin M. ; Nodzyński, Tomasz ; Errafi, Sanae ; Bucher, Rahel ; Gupta, Shibu ; Aryal, Bibek ; Dobrev, Petre ; Bigler, Laurent ; Geisler, Markus ; Zažímalová, Eva ; Friml, Jiří ; Ringli, Christoph

In: Scientific Reports, 2017, vol. 7, p. 41906

The phytohormone auxin is a major determinant and regulatory component important for plant development. Auxin transport between cells is mediated by a complex system of transporters such as AUX1/LAX, PIN, and ABCB proteins, and their localization and activity is thought to be influenced by phosphatases and kinases. Flavonols have been shown to alter auxin transport activity and changes in...

Université de Fribourg

TWISTED DWARF1 mediates the action of auxin transport inhibitors on actin cytoskeleton dynamics

Zhu, Jinsheng ; Bailly, Aurelien ; Zwiewka, Marta ; Sovero, Valpuri ; Donato, Martin Di ; Ge, Pei ; Oehri, Jacqueline ; Aryal, Bibek ; Hao, Pengchao ; Linnert, Miriam ; Burgardt, Noelia Inés ; Lücke, Christian ; Weiwad, Matthias ; Michel, Max ; Weiergräber, Oliver H. ; Pollmann, Stephan ; Azzarello, Elisa ; Mancuso, Stefano ; Ferro, Noel ; Fukao, Yoichiro ; Hoffmann, Céline ; Wedlich-Söldner, Roland ; Friml, Jiří ; Thomas, Clément ; Geisler, Markus

In: The Plant Cell, 2016, vol. 28, no. 4, p. 930–948

Plant growth and architecture is regulated by the polar distribution of the hormone auxin. Polarity and flexibility of this process is provided by constant cycling of auxin transporter vesicles along actin filaments, coordinated by a positive auxin-actin feedback loop. Both polar auxin transport and vesicle cycling are inhibited by synthetic auxin transport inhibitors, such as...