Université de Fribourg

How clonal are clones? A quest for loss of heterozygosity during asexual reproduction in Daphnia magna

Dukić, Marinela ; Berner, Daniel ; Haag, Christoph R. ; Ebert, Dieter

In: Journal of Evolutionary Biology, 2019, vol. 32, no. 6, p. 619–628

Due to the lack of recombination, asexual organisms are predicted to accumulate mutations and show high levels of within‐individual allelic divergence (heterozygosity); however, empirical evidence for this prediction is largely missing. Instead, evidence of genome homogenization during asexual reproduction is accumulating. Ameiotic crossover recombination is a mechanism that could lead to...

Université de Fribourg

A high-density genetic map reveals variation in recombination rate across the genome of Daphnia magna

Dukić, Marinela ; Berner, Daniel ; Roesti, Marius ; Haag, Christoph R. ; Ebert, Dieter

In: BMC Genetics, 2016, vol. 17, p. 137

Recombination rate is an essential parameter for many genetic analyses. Recombination rates are highly variable across species, populations, individuals and different genomic regions. Due to the profound influence that recombination can have on intraspecific diversity and interspecific divergence, characterization of recombination rate variation emerges as a key resource for population...

Université de Fribourg

Uncovering cryptic asexuality in Daphnia magna by RAD sequencing

Svendsen, Nils ; Reisser, Celine M. O. ; Dukić, Marinela ; Thuillier, Virginie ; Ségard, Adeline ; Liautard-Haag, Cathy ; Fasel, Dominique ; Hürlimann, Evelin ; Lenormand, Thomas ; Galimov, Yan ; Haag, Christoph R.

In: Genetics, 2015, vol. 201, no. 3, p. 1143–1155

The breeding systems of many organisms are cryptic and difficult to investigate with observational data, yet they have profound effects on a species’ ecology, evolution, and genome organization. Genomic approaches offer a novel, indirect way to investigate breeding systems, specifically by studying the transmission of genetic information from parents to offspring. Here we exemplify this method...