Université de Fribourg

Effects of an iron-based fuel-borne catalyst and a diesel particle filter on exhaust toxicity in lung cells in vitro

Steiner, Sandro ; Czerwinski, Jan ; Comte, Pierre ; Heeb, Norbert V. ; Mayer, Andreas ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Analytical and Bioanalytical Chemistry, 2015, vol. 407, no. 20, p. 5977–5986

Metal-containing fuel additives catalyzing soot combustion in diesel particle filters are used in a widespread manner, and with the growing popularity of diesel vehicles, their application is expected to increase in the near future. Detailed investigation into how such additives affect exhaust toxicity is therefore necessary and has to be performed before epidemiological evidence points towards...

Université de Fribourg

Reduction in (pro-)inflammatory responses of lung cells exposed in vitro to diesel exhaust treated with a non-catalyzed diesel particle filter

Steiner, Sandro ; Czerwinski, Jan ; Comte, Pierre ; Müller, Loretta L. ; Heeb, Norbert V. ; Mayer, Andreas ; Petri-Fink, Alke ; Rothen-Rutishauser, Barbara

In: Atmospheric Environment, 2013, vol. 81, p. 117–124

Increasingly stringent regulation of particulate matter emissions from diesel vehicles has led to the widespread use of diesel particle filters (DPFs), the effect of which on exhaust toxicity is so far poorly understood. We exposed a cellular model of the human respiratory epithelium at the air-liquid interface to non-catalyzed wall-flow DPF-filtered diesel exhaust and compared the resulting...