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    Université de Fribourg

    National survey of colistin resistance among carbapenemase-producing Enterobacteriaceae and outbreak caused by colistin-resistant OXA-48-producing Klebsiella pneumoniae , France, 2014

    Jayol, Aurélie ; Poirel, Laurent ; Dortet, Laurent ; Nordmann, Patrice

    In: Eurosurveillance, 2016, vol. 21, no. 37, p. -

    From January 2014 to December 2014, 972 consecutive non-replicate carbapenemase-producing Enterobacteriaceae isolates from colonised or infected patients were collected at the Associated French National Reference Centre as part of the French national survey on antimicrobial resistance. It included 577 Klebsiella spp. (59%), 236 Escherichia coli (24%), 108 Enterobacter spp. (11%), 50...

    Université de Fribourg

    Strategy for a rapid detection of carbapenemase-producing Enterobacteriaceae

    Dortet, Laurent ; Bréchard, Ludivine ; Cuzon, Gaëlle ; Poirel, Laurent ; Nordmann, Patrice

    In: Antimicrobial Agents and Chemotherapy, 2014, vol. 58, no. 4, p. 2441-2445

    A prospective survey was conducted on 862 Enterobacteriaceae with reduced susceptibility to carbapenems. The Carba NP test, UV spectrophotometry and DNA microarray were used for detecting carbapenemase producers, and results compared to PCR and sequencing. The 172 carbapenemase producers were detected using the Carba NP test and UV spectrophotometry whereas DNA microarray failed to detect IMI...