In: Brain Structure and Function, 2012, vol. 217, no. 1, p. 63-79
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In: Brain Structure and Function, 2011, vol. 217, no. 1, p. 63-79
Although the arrangement of the corticospinal projection in primates is consistent with a more prominent role of the ipsilateral motor cortex on proximal muscles, rather than on distal muscles involved in manual dexterity, the role played by the primary motor cortex on the control of manual dexterity for the ipsilateral hand remains a matter a debate, either in the normal function or after a...
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In: Neurosurgery, 2011, vol. 68, no. 5, p. 1405-1417
BACKGROUND: Although cell therapy is a promising approach after cerebral cortex lesion, few studies assess quantitatively its behavioral gain in nonhuman primates. Furthermore, implantations of fetal grafts of exogenous stem cells are limited by safety and ethical issues.OBJECTIVE: To test in nonhuman primates the transplantation of autologous adult neural progenitor cortical cells with...
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In: Journal of Neurophysiology, 2010, p. -
Manual dexterity, a prerogative of primates, is under the control of the corticospinal (CS) tract. As 90-95% of CS axons decussate, it is assumed that this control is exerted essentially on the contralateral hand. Consistently, unilateral lesion of the hand representation in the motor cortex is followed by a complete loss of dexterity of the contralesional hand. During the months following...
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