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Disinhibition of neurite growth to repair the injured adult CNS: Focusing on Nogo

Gonzenbach, R. ; Schwab, M.

In: Cellular and Molecular Life Sciences, 2008, vol. 65, no. 1, p. 161-176

Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury

Maier, Irin C. ; Ichiyama, Ronaldo M. ; Courtine, Grégoire ; Schnell, Lisa ; Lavrov, Igor ; Edgerton, V. Reggie ; Schwab, Martin E.

In: Brain, 2009, vol. 132, no. 6, p. 1426-1440

Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Séquard syndrome

Filli, Linard ; Zörner, Björn ; Weinmann, Oliver ; Schwab, Martin E.

In: Brain, 2011, vol. 134, no. 8, p. 2261-2273

Heterogeneous Spine Loss in Layer 5 Cortical Neurons after Spinal Cord Injury

Ghosh, Arko ; Peduzzi, Stefano ; Snyder, Moina ; Schneider, Regula ; Starkey, Michelle ; Schwab, Martin E.

In: Cerebral Cortex, 2012, vol. 22, no. 6, p. 1309-1317

Repair of the injured spinal cord, a joint approach of basic and clinical research

Buchli, Anita D. ; Rouiller, Eric M. ; Mueller, Roland ; Dietz, Volker ; Schwab, Martin E.

In: Neurodegenerative Diseases, 2007, vol. 4, no. 1, p. 51-56

The myelin protein Nogo-A is a potent inhibitor of neurite outgrowth in the central nervous system, thus contributing to the incapacity of fiber tracts in the adult spinal cord to regenerate after injury. In this review we report on a joint approach of different research groups to develop a therapy applying anti-Nogo-A antibodies to the injured spinal cord. While basic researchers took the...