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The role of Nogo-A in axonal plasticity, regrowth and repair

Pernet, Vincent ; Schwab, Martin

In: Cell and Tissue Research, 2012, vol. 349, no. 1, p. 97-104

Differential effects of anti-Nogo-A antibody treatment and treadmill training in rats with incomplete spinal cord injury

Maier, Irin C. ; Ichiyama, Ronaldo M. ; Courtine, Grégoire ; Schnell, Lisa ; Lavrov, Igor ; Edgerton, V. Reggie ; Schwab, Martin E.

In: Brain, 2009, vol. 132, no. 6, p. 1426-1440

Nogo-a regulates neural precursor migration in the embryonic mouse cortex

Mathis, C.

In: Cerebral Cortex, 2010, vol. 20, no. 10, p. 2380-2390

Repair of the injured spinal cord, a joint approach of basic and clinical research

Buchli, Anita D. ; Rouiller, Eric M. ; Mueller, Roland ; Dietz, Volker ; Schwab, Martin E.

In: Neurodegenerative Diseases, 2007, vol. 4, no. 1, p. 51-56

The myelin protein Nogo-A is a potent inhibitor of neurite outgrowth in the central nervous system, thus contributing to the incapacity of fiber tracts in the adult spinal cord to regenerate after injury. In this review we report on a joint approach of different research groups to develop a therapy applying anti-Nogo-A antibodies to the injured spinal cord. While basic researchers took the...