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Université de Neuchâtel

Evolution of the "Castanea sativa" - "Dryocosmus kuriphilus" - "Torymus sinensis" - system in southern Switzerland

Gehring, Eric ; Aebi, Alexandre (Dir.) ; Conedera, Marco (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

The arrival of new organisms that may potentially become harmful for people and ecosystems has become a world-wide daily concern to the point that in Switzerland about 800 established alien species exist, of which at least 107 are considered invasive. A possible way to control such pests is by importing and releasing natural enemies from their countries of origin, letting them to act as so-called...

Université de Fribourg

A substantial discount on ski passes : a synthetic control analysis

Wallimann, Hannes

(Working Papers SES ; 507)

The synthetic control method serves as an appropriate and promising approach to do quantitative comparison research. However, the method is rarely used in the context of tourism. We fill this research gap by applying the method to the case of a Swiss mountain destination. Alpine tourist destinations have suffered from a declining demand in the last decade. Fewer tourist visit ski resorts....

Université de Neuchâtel

Ecosystem engineers’ contribution to soil structure formation in floodplains

Schomburg, Andreas ; Le Bayon, Claire (Dir.) ; Guenat, Claire (Codir.) ; Brunner, Philip (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

Soil structure formation constitutes an extremely important process in near-natural and restored floodplains. A stable soil structure protects riverbanks from erosion and contributes to the preservation of ecosystem services. However, developing a soil structure in alluvial soils is difficult for several reasons. Extensive alluvial dynamics cause periodic waterlogging and continuously rejuvenate...

Université de Fribourg

The PARP inhibitor olaparib exerts beneficial effects in mice subjected to cecal ligature and puncture and in cells subjected to oxidative stress without impairing DNA integrity: A potential opportunity for repurposing a clinically used oncological drug for the experimental therapy of sepsis

Ahmad, Akbar ; Vieira, Juliana de Camargo ; Mello, Aline Haas de ; Lima, Thais Martins de ; Ariga, Suely Kubo ; Barbeiro, Denise Frediani ; Barbeiro, Hermes Vieira ; Szczesny, Bartosz ; Törö, Gábor ; Druzhyna, Nadiya ; B.Randi, Elisa ; Marcatti, Michela ; Toliver-Kinsky, Tracy ; Kiss, András ; Liaudet, Lucas ; Salomao, Reinaldo ; Soriano, Francisco Garcia ; Szabo, Csaba

In: Pharmacological Research, 2019, vol. 145, p. 104263

Poly(ADP-ribose) polymerase (PARP) is involved in the pathogenesis of cell dysfunction, inflammation and organ failure during septic shock. The goal of the current study was to investigate the efficacy and safety of the clinically approved PARP inhibitor olaparib in experimental models of oxidative stress in vitro and in sepsis in vivo. In mice subjected to cecal ligation and puncture (CLP)...

Université de Neuchâtel

New frontiers of ultrafast thin-disk laser oscillators for applications in metrology and the generation of THz and XUV radiation

Modsching, Norbert Paul ; Südmeyer, Thomas (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

Ultrafast laser systems find application as versatile tool in industry and science. Ultrafast laser systems based on Ti:sapphire – the workhorse in ultrafast science – operate typically at kHz repetition rates and benefit from the available broad gain bandwidth for the direct generation of sub 100-fs pulse durations. However, thermal effects in the gain medium due to a high quantum defect...

Università della Svizzera italiana

Proteostasis : bad news and good news from the endoplasmic reticulum

Noack, Julia ; Brambilla Pisoni, Giorgia ; Molinari, Maurizio

In: Swiss medical weekly, 2014, vol. 144, p. w14001

The endoplasmic reticulum (ER) is an intracellular compartment dedicated to the synthesis and maturation of secretory and membrane proteins, totalling about 30% of the total eukaryotic cells proteome. The capacity to produce correctly folded polypeptides and to transport them to their correct intra- or extracellular destinations relies on proteostasis networks that regulate and balance the...

Université de Neuchâtel

Rubidium vapour-cell frequency standards : metrology of optical and microwave frequency references

Moreno, William ; Mileti, Gaetano (Dir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

This thesis concerns the development, study, and optimisation of compact and high-performance frequency references based on rubidium (Rb) vapour cells1. More specially, two Rb vapour-cell frequency references are studied: an optical-frequency reference at 1.5 μm and a double-resonance pulsed optically pumped (POP) atomic clock. The use of vapour cells allows compact frequency...