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    Université de Fribourg

    Variation in thermal performance and reaction norms among populations of Drosophila melanogaster

    Klepsatel, Peter ; Gáliková, Martina ; De Maio, Nicola ; Huber, Christian D. ; Schlötterer, Christian ; Flatt, Thomas

    In: Evolution, 2013, vol. 67, no. 12, p. 3573–3587

    The major goal of evolutionary thermal biology is to understand how variation in temperature shapes phenotypic evolution. Comparing thermal reaction norms among populations from different thermal environments allows us to gain insights into the evolutionary mechanisms underlying thermal adaptation. Here, we have examined thermal adaptation in six wild populations of the fruit fly (Drosophila...

    Université de Fribourg

    Steroid hormone regulation of C. elegans and Drosophila aging and life history

    Gáliková, Martina ; Klepsatel, Peter ; Senti, Gabriele ; Flatt, Thomas

    In: Experimental Gerontology, 2011, vol. 46, no. 2, p. 141–147

    In the last two decades it has become clear that hormones and gene mutations in endocrine signaling pathways can exert major effects on lifespan and related life history traits in worms, flies, mice, and other organisms. While most of this research has focused on insulin/insulin-like growth factor-1 signaling, a peptide hormone pathway, recent work has shown that also lipophilic hormones play...