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Université de Fribourg

Remote sensing of cropping practice in Northern Italy using time-series from Sentinel-2

Ottosen, Thor-Bjørn ; Lommen, Suzanne T.E. ; Skjøth, Carsten Ambelas

In: Computers and Electronics in Agriculture, 2019, vol. 157, p. 232–238

Maps of cropping practice, including the level of weed infestation, are useful planning tools e.g. for the assessment of the environmental impact of the crops, and Northern Italy is an important example due to the large and diverse agricultural production and the high weed infestation. Sentinel-2A is a new satellite with a high spatial and temporal resolution which potentially allows the...

Université de Fribourg

The metalloprotease ADAMTS4 generates N-truncated Aβ4–x species and marks oligodendrocytes as a source of amyloidogenic peptides in Alzheimer’s disease

Walter, Susanne ; Jumpertz, Thorsten ; Hüttenrauch, Melanie ; Ogorek, Isabella ; Gerber, Hermeto ; Storck, Steffen E. ; Zampar, Silvia ; Dimitrov, Mitko ; Lehmann, Sandra ; Lepka, Klaudia ; Berndt, Carsten ; Wiltfang, Jens ; Becker-Pauly, Christoph ; Beher, Dirk ; Pietrzik, Claus U. ; Fraering, Patrick C. ; Wirths, Oliver

In: Acta Neuropathologica, 2019, vol. 137, no. 2, p. 239–257

Brain accumulation and aggregation of amyloid-β (Aβ) peptides is a critical step in the pathogenesis of Alzheimer’s disease (AD). Full-length Aβ peptides (mainly Aβ1–40 and Aβ1–42) are produced through sequential proteolytic cleavage of the amyloid precursor protein (APP) by β- and γ-secretases. However, studies of autopsy brain samples from AD patients have demonstrated that a...

Université de Neuchâtel

El ritmo acentual en treinta y tres romances de juventud atribuidos a Lope de Vega

Llamas Martínez, Jacobo ; Sánchez Jiménez, Antonio (Dir.) ; Matas Caballero, Juan (Codir.) ; Navarro Colorado, Borja (Codir.) ; Udaondo Alegre, Juan (Codir.)

Thèse de doctorat : Université de Neuchâtel, 2019.

Cette thèse est basée sur une affirmation de Lope dans le prologue des Rimas de 1604 sur la «corresponsión de las cadencias » de ses romances ; la déclaration semble faire référence à une difficulté technique liée à la distribution des accents et dans laquelle les « gente ignorante » ne réparent généralement pas. Pour résoudre les deux questions, si Lope a fait allusion à une...

Università della Svizzera italiana

Homeostatic expansion of autoreactive immunoglobulin-secreting cells in the Rag2 mouse model of Omenn syndrome

Cassani, Barbara ; Poliani, Pietro Luigi ; Marrella, Veronica ; Schena, Francesca ; Sauer, Aisha V. ; Ravanini, Maria ; Strina, Dario ; Busse, Christian E. ; Regenass, Stephan ; Wardemann, Hedda ; Martini, Alberto ; Facchetti, Fabio ; Burg, Mirjam van der ; Rolink, Antonius G. ; Vezzoni, Paolo ; Grassi, Fabio ; Traggiai, Elisabetta ; Villa, Anna

In: Journal of experimental medicine, 2010, vol. 207, no. 7, p. 1525-1540

Hypomorphic RAG mutations, leading to limited V(D)J rearrangements, cause Omenn syndrome (OS), a peculiar severe combined immunodeficiency associated with autoimmune-like manifestations. Whether B cells play a role in OS pathogenesis is so far unexplored. Here we report the detection of plasma cells in lymphoid organs of OS patients, in which circulating B cells are undetectable. Hypomorphic...

Université de Fribourg

A resazurin reduction-based assay for rapid detection of polymyxin resistance in Acinetobacter baumannii and Pseudomonas aeruginosa

Lescat, Mathilde ; Poirel, Laurent ; Tinguely, Camille ; Nordmann, Patrice

In: Journal of Clinical Microbiology, 2018, p. -

A rapid test was developed for identification of polymyxin resistance in non-fermenting bacteria. This test detects viable cells after growth in a medium containing a defined concentration of colistin. The principle of this test is based on the visual detection of the reduction of the resazurin reagent, a viability colorant, observed by its color change (blue to purple or pink). Its...

Université de Fribourg

Comparative study of nonequilibrium insulator-to-metal transitions in electron-phonon systems

Sayyad, Sharareh ; Žitko, Rok ; Strand, Hugo U. R. ; Werner, Philipp ; Golež, Denis

In: Physical Review B, 2019, vol. 99, no. 4, p. 045118

We study equilibrium and nonequilibrium properties of electron-phonon systems described by the Hubbard-Holstein model using dynamical mean-field theory. In equilibrium, we benchmark the results for impurity solvers based on the one-crossing approximation and slave-rotor approximation against non-perturbative numerical renormalization group reference data. We also examine how well the...

Université de Fribourg

Predicting perceptions of the lexical richness of short French, German, and Portuguese texts using text-based indices

Vanhove, Jan ; Bonvin, Audrey ; Lambelet, Amelia ; Berthele, Raphael

In: Journal of Writing Research, 2019, vol. 10, no. 3, p. 499-525

We investigated how well readers’ perceptions of the lexical richness of short texts can be predicted on the basis of automatically computable indices of the texts’ lexical properties. 3,060 French, German and Portuguese texts (between 9 and 284 words long) written by 8- to 10-year-olds were rated for their lexical richness by between 3 and 18 uninstructed raters, and over 150 indices were...

Université de Fribourg

The reproducibility of SfM algorithms to produce detailed Digital Surface Models: the example of PhotoScan applied to a high-alpine rock glacier

Hendrickx, Hanne ; Vivero, Sebastián ; Cock, Laure De ; De Wit, Bart ; De Maeyer, Philippe ; Lambiel, Christophe ; Delaloye, Reynald ; Nyssen, Jan ; Frankl, Amaury

In: Remote Sensing Letters, 2019, vol. 10, no. 1, p. 11–20

In geomorphology, PhotoScan is a software that is used to produce Digital Surface Models (DSMs). It constructs 3D environments from 2D imagery (often taken by Unmanned Aerial Vehicles (UAV)) based on Structure-from-Motion (SfM) and Multi- View Stereo (MVS) principles. However, unpublished computer-vision algorithms used, contain random elements which can affect the accuracy of the outputs. For...

Haute Ecole de Gestion & Tourisme

Analysis, design, and implementation of an infrastructure-less situation awareness application

Bonvin, Flavien ; Bocchi, Yann (Dir.)

Mémoire de bachelor : Haute Ecole de Gestion & Tourisme, 2018.

This work aims to implement an application based on opportunistic communication. It must be operational in a disaster situation when the cellular network is not available. During this work, a first part was consecrated to the study of the several types of ad hoc networks and the various technologies related to them. This has served as a foundation for the study of ad hoc networks in...

Université de Fribourg

Microglia at center stage: a comprehensive review about the versatile and unique residential macrophages of the central nervous system

Lannes, Nils ; Eppler, Elisabeth ; Etemad, Samar ; Yotovski, Peter ; Filgueira, Luis

In: Oncotarget, 2017, vol. 8, no. 69, p. 114393–114413

Microglia cells are the unique residential macrophages of the central nervous system (CNS). They have a special origin, as they derive from the embryonic yolk sac and enter the developing CNS at a very early stage. They play an important role during CNS development and adult homeostasis. They have a major contribution to adult neurogenesis and neuroinflammation. Thus, they participate in the...