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    Université de Fribourg

    Quantification of multiple bile acids in uninephrectomized rats using ultra-performance liquid chromatography-tandem mass spectrometry

    Penno, Carlos A. ; Arsenijevic, Denis ; Cunha, Thierry Da ; Kullak-Ublic, Gerd A. ; Montani, Jean-Pierre ; Odermatt, Alex

    In: Analytical Methods, 2013, vol. 5, p. 1155-1164

    In order to study the roles of individual BAs and due to limited blood sample volumes available from experimental animals, improved methods for the simultaneous quantification of multiple BAs are needed. We developed and validated an ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the quantification of 24 BAs, including 11 unconjugated, 6...