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    Université de Fribourg

    A role for skeletal muscle stearoyl-CoA desaturase 1 in control of thermogenesis

    Mainieri, Davide ; Summermatter, Serge ; Seydoux, Josiane ; Montani, Jean-Pierre ; Rusconi, Sandro ; Russell, Aaron P. ; Boss, Olivier ; Buchala, Antony J. ; Dulloo, Abdul G.

    In: The FASEB Journal, 2006, vol. 20, no. 10, p. 1751-1753

    An enhanced metabolic efficiency for accelerating the recovery of fat mass (or catch-up fat) is a characteristic feature of body weight regulation after weight loss or growth retardation and is the outcome of an "adipose-specific" suppression of thermogenesis, i.e., a feedback control system in which signals from the depleted adipose tissue fat stores exert a suppressive effect on thermogenesis....