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The mammalian circadian timing system: organization and coordination of central and peripheral clocks

Dibner, Charna ; Schibler, Ueli ; Albrecht, Urs

In: Annual Review of Physiology, 2010, vol. 72, p. 517-549

Most physiology and behavior of mammalian organisms follow daily oscillations. These rhythmic processes are governed by environmental cues (e.g., fluctuations in light intensity and temperature), an internal circadian timing system, and the interaction between this timekeeping system and environmental signals. In mammals, the circadian timekeeping system has a complex architecture, composed of a...