Refine my results

Immature large ribosomal subunits containing the 7S pre-rRNA can engage in translation in Saccharomyces cerevisiae

Rodríguez-Galán, Olga ; García-Gómez, Juan J ; Kressler, Dieter ; Cruz, Jesús de la

In: RNA Biology, 2015, vol. 12, no. 8, p. 838–846

Evolution has provided eukaryotes with mechanisms that impede immature and/or aberrant ribosomes to engage in translation. These mechanisms basically either prevent the nucleo-cytoplasmic export of these particles or, once in the cytoplasm, the release of associated assembly factors, which interfere with the binding of translation initiation factors and/or the ribosomal subunit joining. We have...