Université de Fribourg

Hold on to your friends: dedicated chaperones of ribosomal proteins

Pillet, Benjamin ; Mitterer, Valentin ; Kressler, Dieter ; Pertschy, Brigitte

In: BioEssays, 2017, vol. 39, no. 1, p. -

Eukaryotic ribosomes are assembled from their components, the ribosomal RNAs and ribosomal proteins, in a tremendously complex, multi-step process, which primarily takes place in the nuclear compartment. Therefore, most ribosomal proteins have to travel from the cytoplasm to their incorporation site on pre-ribosomes within the nucleus. However, due to their particular characteristics, such as...