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Yar1 protects the ribosomal protein rps3 from aggregation

Koch, Barbara ; Mitterer, Valentin ; Niederhauser, Johannes ; Stanborough, Tamsyn ; Murat, Guillaume ; Rechberger, Gerald ; Bergler, Helmut ; Kressler, Dieter ; Pertschy, Brigitte

In: The journal of Biological Chemistry, 2012, p. -

2000 ribosomes have to be synthesized in yeast every minute. Therefore the fast production of ribosomal proteins, their efficient delivery to the nucleus and correct incorporation into ribosomal subunits are prerequisites for optimal growth rates. Here, we report that the ankyrin repeat protein Yar1 directly interacts with the small ribosomal subunit protein Rps3 and accompanies newly synthesized...