Refine my results

Document type

Institution

Specific Collection

Language

Keyword

Université de Fribourg

De novo expression of parvalbumin in ependymal cells in response to brain injury promotes ependymal remodeling and wound repair

Szabolcsi, Viktória ; Celio, Marco R.

In: Glia, 2014, p. -

The calcium-binding protein parvalbumin (PV) hallmarks subpopulations of interneurons in the murine brain. We serendipitously observed the de novo expression of PV in ependymal cells of the lateral ventricle wall following in vivo lesioning and brain slicing for the preparation of organotypic hippocampal slice cultures (OHSCs). In OHSCs, de novo PV-expression begins shortly after the onset of...

  • In other instances, PVimmunoreactivity did not prevent neuronal cell death (Dijk and Kamphuis, 2004; Maetzler et al., 2004)....
  • Maetzler W, Nitsch C, Bendfeldt K, Racay P, Vollenweider F, Schwaller B. 2004....
Université de Fribourg

Microcalcification after excitotoxicity is enhanced in transgenic mice expressing parvalbumin in all neurones, may commence in neuronal mitochondria and undergoes structural modifications over time

Maetzler, W. ; Stünitz, H. ; Bendfeldt, Kerstin ; Vollenweider, F. ; Schwaller, Beat ; Nitsch, C.

In: Neuropathology and Applied Neurobiology, 2009, vol. 35, no. 2, p. 165 - 177

Aims: Parenchymal microcalcification in the brain coincides with neurodegenerative diseases, but is also frequently found in neurologically normal individuals. The origin and role of this process are still under debate. Parvalbumin (PV) is a protein acting as a Ca2+ buffer and Ca2+ shuttle towards intracellular Ca2+ sinks, like mitochondria and the endoplasmic reticulum. Constitutively, it is...

  • Maetzler*†, H....
  • Neuroscience 2006; 142: 97–105 22 Maetzler W, Nitsch C, Bendfeldt K, Racay P, Vollenweider F, Schwaller B....