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Imaging magnetic nanoparticle distributions by atomic magnetometry-based susceptometry

Colombo, Simone ; Lebedev, Victor ; Tonyushkin, Alexey ; Pengue, Simone ; Weis, Antoine

In: IEEE Transactions on Medical Imaging, 2020, vol. 39, no. 4, p. 922–933

We introduce a Magnetic Particle Imaging Susceptometer (MPIS) that uses a high- sensitivity atomic magnetometer (AM) for recording the spatial distribution of fluid- suspended magnetic nanoparticles. We have evaluated the MPIS performance by one-dimensional scans of structured nanoparticle phantoms, demonstrating, in particular, resolutions of ≈2.5 mm prior to deconvolution and ≪1 mm after ...