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Control of cellular physiology by TM9 proteins in yeast and Dictyostelium

Froquet, Romain ; Cherix, Nathalie ; Birke, Raphael ; Benghezal, Mohammed ; Cameroni, Elisabetta ; Letourneur, François ; Mösch, Hans-Ulrich ; De Virgilio, Claudio ; Cosson, Pierre

In: Journal of Biological Chemistry, 2008, vol. 283, no. 11, p. 6764-6772

TM9 proteins constitute a well defined family, characterized by the presence of a large variable extracellular domain and nine putative transmembrane domains. This family is highly conserved throughout evolution and comprises three members in Dictyostelium discoideum and Saccharomyces cerevisiae and four in humans and mice. In Dictyostelium, previous analysis demonstrated...