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Université de Fribourg

In vivo deployment of mechanically adaptive nanocomposites for intracortical microelectrodes

Harris, J. P. ; Hess, Andreas E. ; Rowan, Stuart J. ; Weder, Christoph ; Zorman, C. A. ; Tyler, D. J. ; Capadona, Jeffrey R.

In: Journal of Neural Engineering, 2011, vol. 8, no. 4, p. 046010

We recently introduced a series of stimuli-responsive, mechanically adaptive polymer nanocomposites. Here, we report the first application of these bio-inspired materials as substrates for intracortical microelectrodes. Our hypothesis is that the ideal electrode should be initially stiff to facilitate minimal trauma during insertion into the cortex, yet become mechanically compliant to match the...

Université de Fribourg

Development of a stimuli-responsive polymer nanocomposite toward biologically optimized, MEMS-based neural probes

Hess, Andreas E. ; Capadona, Jeffrey R. ; Shanmuganathan, Kadhiravan ; Hsu, L. ; Rowan, Suart J. ; Weder, Christoph ; Tyler, D. J. ; Zorman, C. A.

In: Journal of Micromechanics and Microengineering, 2011, vol. 21, no. 5, p. 054009

This paper reports the development of micromachining processes and mechanical evaluation of a stimuli-responsive, mechanically dynamic polymer nanocomposite for biomedical microsystems. This nanocomposite consists of a cellulose nanofiber network encased in a polyvinyl acetate matrix. Micromachined tensile testing structures fabricated from the nanocomposite displayed a reversible and switchable...