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Methylation profile of TP53 regulatory pathway and mtDNA alterations in breast cancer patients lacking TP53 mutations

Barekati, Zeinab ; Radpour, Ramin ; Kohler, Corina ; Zhang, Bei ; Toniolo, Paolo ; Lenner, Per ; Lv, Qing ; Zheng, Hong ; Zhong, Xiao Yan

In: Human Molecular Genetics, 2010, vol. 19, no. 15, p. 2936-2946

HG-11INTEGRATIVE MOLECULAR META-ANALYSIS OF 700 PEDIATRIC HIGH GRADE GLIOMA AND DIPG DEFINES WIDESPREAD INTER- AND INTRA-TUMORAL HETEROGENEITY

Mackay, Alan ; Vinci, Mara ; Burford, Anna ; Bjerke, Lynn ; Taylor, Katy ; Nandhabalan, Meera ; Marshall, Lynley ; Molinari, Valeria ; Popov, Sergey ; Ingram, Wendy ; Moore, Andrew ; Trabelsi, Saoussen ; Hmida, Dorra ; Mu, Kun ; Bidinotto, Lucas ; Reis, Rui ; Ng, H.K. ; von Bueren, Andre ; Baudis, Michael ; Jones, Chris

In: Neuro-Oncology, 2015, vol. 17, p. iii12-iii13

Promoter methylation of the DNA repair gene MGMT in astrocytomas is frequently associated with G:C → A:T mutations of the TP53 tumor suppressor gene

Nakamura, Mitsutoshi ; Watanabe, Takao ; Yonekawa, Yasuhiro ; Kleihues, Paul ; Ohgaki, Hiroko

In: Carcinogenesis, 2001, vol. 22, no. 10, p. 1715-1719

Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells

Chatagnon, Amandine ; Bougel, Stéphanie ; Perriaud, Laury ; Lachuer, Joël ; Benhattar, Jean ; Dante, Robert

In: Carcinogenesis, 2008, vol. 30, no. 1, p. 28-34

Chromatin structure and methylation of rat rRNA genes studied by formaldehyde fixation and psoralen cross-linking

Stancheva, Irina ; Lucchini, Renzo ; Koller, Theodor ; Sogo, José M.

In: Nucleic Acids Research, 1997, vol. 25, no. 9, p. 1727-1735

siRNAs from miRNA sites mediate DNA methylation of target genes

Chellappan, Padmanabhan ; Xia, Jing ; Zhou, Xuefeng ; Gao, Shang ; Zhang, Xiaoming ; Coutino, Gabriela ; Vazquez, Franck ; Zhang, Weixiong ; Jin, Hailing

In: Nucleic Acids Research, 2010, vol. 38, no. 20, p. 6883-6894

Immunosuppressive mechanisms in glioblastoma

Nduom, E K.

In: Neuro-Oncology, 2015, vol. 17, p. vii9-vii14

Gross total but not incomplete resection of glioblastoma prolongs survival in the era of radiochemotherapy†

Kreth, F. -W ; Thon, N. ; Simon, M. ; Westphal, M. ; Schackert, G. ; Nikkhah, G. ; Hentschel, B. ; Reifenberger, G. ; Pietsch, T. ; Weller, M. ; Tonn, J. -C

In: Annals of Oncology, 2013, vol. 24, no. 12, p. 3117-3123

Two cilengitide regimens in combination with standard treatment for patients with newly diagnosed glioblastoma and unmethylated MGMT gene promoter: results of the open-label, controlled, randomized phase II CORE study

Nabors, L. Burt ; Fink, Karen L. ; Mikkelsen, Tom ; Grujicic, Danica ; Tarnawski, Rafal ; Nam, Do Hyun ; Mazurkiewicz, Maria ; Salacz, Michael ; Ashby, Lynn ; Zagonel, Vittorina ; Depenni, Roberta ; Perry, James R. ; Hicking, Christine ; Picard, Martin ; Hegi, Monika E. ; Lhermitte, Benoit ; Reardon, David A.

In: Neuro-Oncology, 2015, vol. 17, no. 5, p. 708-717

Histone methylation in the nervous system : functions and dysfunctions

Pattaroni, Céline ; Jacob, Claire

In: Molecular Neurobiology, 2013, vol. 47, no. 2, p. 740-756

Chromatin remodeling is a key epigenetic process controlling the regulation of gene transcription. Local changes of chromatin architecture can be achieved by post-translational modifications of histones such as methylation, acetylation, phosphorylation, ubiquitination, sumoylation, and ADP-ribosylation. These changes are dynamic and allow for rapid repression or de-repression of specific target...