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Université de Fribourg

Ex vivo analysis of kidney graft viability using 31p magnetic resonance imaging spectroscopy

Longchamp, Alban ; Klauser, Antoine ; Songeon, Julien ; Agius, Thomas ; Nastasi, Antonio ; Ruttiman, Raphael ; Moll, Solange ; Meier, Raphael P. H. ; Buhler, Leo ; Corpataux, Jean-Marc ; Lazeyras, Francois

In: Transplantation, 2020, vol. 104, no. 9, p. 1825–1831

Background: The lack of organs for kidney transplantation is a growing concern. Expansion in organ supply has been proposed through the use of organs after circulatory death (donation after circulatory death [DCD]). However, many DCD grafts are discarded because of long warm ischemia times, and the absence of reliable measure of kidney viability. 31P magnetic resonance imaging (pMRI)...

Haute Ecole pédagogique Fribourg

Une typologie des traces numériques utilisées par de futurs enseignants = A typology of digital traces used by future teachers

Coen, Pierre-François ; Bouzenada Sottas, Céline

In: Questions vives, 2019, no. 31, p. 1-19

Afin de construire des liens entre théorie et pratique et développer leurs capacités autoévaluatives et leur réflexivité, les étudiants de la Haute école pédagogique de Fribourg (HEPFR) doivent élaborer un dossier d’apprentissage (DAP). Ainsi, ils sont incités à collecter des traces (photos, vidéos, papier) de leurs activités (en particulier lorsqu’ils sont en stage sur le...

Université de Fribourg

Targeting the extra-cellular matrix—tumor cell crosstalk for anti-cancer therapy: emerging alternatives to integrin inhibitors

Lorusso, Girieca ; Rüegg, Curzio ; Kuonen, François

In: Frontiers in Oncology, 2020, vol. 10, p. -

The extracellular matrix (ECM) is a complex network composed of a multitude of different macromolecules. ECM components typically provide a supportive structure to the tissue and engender positional information and crosstalk with neighboring cells in a dynamic reciprocal manner, thereby regulating tissue development and homeostasis. During tumor progression, tumor cells commonly modify and...

Université de Fribourg

Body composition-derived BMI cut-offs for overweight and obesity in ethnic Indian and Creole urban children of Mauritius

Ramuth, Harris ; Hunma, Sadhna ; Ramessur, Vinaysing ; Ramuth, Magalutcheemee ; Monnard, Cathriona ; Montani, Jean-Pierre ; Schutz, Yves ; Joonas, Noorjehan ; Dulloo, Abdul G.

In: British Journal of Nutrition, 2020, vol. 124, no. 5, p. 481–492

It is increasingly recognised that the use of BMI cut-off points for diagnosing obesity (OB) and proxy measures for body fatness in a given population needs to take into account the potential impact of ethnicity on the BMI–fat % relationship in order to avoid adiposity status misclassification. This relationship was studied here in 377 Mauritian schoolchildren (200 boys and 177 girls, aged...

Université de Fribourg

Lentiviral-mediated up-regulation of let-7d microRNA decreases alcohol intake through down-regulating the dopamine D3 receptor

Bahi, Amine ; Dreyer, Jean-Luc

In: European Neuropsychopharmacology, 2020, vol. 37, p. 70–81

Recent studies have shown that Lethal-7 (let-7) microRNA (miRNA) is involved in a wide range of psychiatric disorders such as anxiety, depression, schizophrenia, and cocaine addiction. However, the exact role of let-7d miRNA in regulating ethanol intake and preference remains to be elucidated. The aim of the present study was to clarify the role of accumbal let-7d in controlling...

Public access from 1-set-2022
Université de Neuchâtel

Social (un-)learning and the legitimization of marginalized knowledge: How a new community of practice tries to ‘kick the grain habit’ in ruminant livestock farming

Vetter, Thomas

In: Journal of Rural Studies, 2020, vol. 79, p. 11-23

This paper presents a qualitative case study analysis of the Pasture-Fed Livestock Association (PFLA), which seeks to ‘kick the grain habit’ in ruminant farming by promoting and certifying purely pasture-fed production systems. Reading through a social learning perspective, the article first traces back how this association has become established as a new and distinct community of practice...

Haute Ecole pédagogique Fribourg

Grounding Social Foundations for Integrated Assessment Models of Climate Change

Mathias, Jean-Denis ; Debeljak, Marko ; Deffuant, Guillaume ; Diemer, Arnaud ; Dierickx Florian ; Donges, Jonathan F. ; Gladkykh, Ganna ; Heitzig, Jobst ; Holtz, Georg ; Obergassel, Wolfgang ; Pellaud, Francine ; Sanchez, Angel ; Trajanov, Aneta ; Videira, Nuno

In: AGU Advancing Earth and Space Science, 2020, vol. 8, no. 7, p. 1-5

Integrated assessment models (IAMs) are commonly used by decision makers in order to derive climate policies. IAMs are currently based on climate‐economics interactions, whereas the role of social system has been highlighted to be of prime importance on the implementation of climate policies. Beyond existing IAMs, we argue that it is therefore urgent to increase efforts in the integration of...

Université de Fribourg

Unexpected presence of 14C in inorganic pigment for an absolute dating of paintings

Beck, Lucile ; Messager, Cyrielle ; Caffy, Ingrid ; Delqué-Količ, Emmanuelle ; Perron, Marion ; Dumoulin, Jean-Pascal ; Moreau, Christophe ; Degrigny, Christian ; Serneels, Vincent

In: Scientific Reports, 2020, vol. 10, no. 1, p. 9582

The absolute dating of paintings is crucial for tackling the problem of fake art. Investigations to authenticate paintings rely on an advanced knowledge of art history and a collection of scientific techniques. Radiocarbon dating is the only technique that gives access to an absolute time scale, but its application is limited to organic materials such as wood, canvas or natural binder....