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Università della Svizzera italiana

A psychometric analysis of the Daily Drinking Questionnaire in a nationally representative sample of young adults from a Mediterranean drinking culture

Piumatti, G. ; Aresi, G. ; Marta, E.

In: Journal of ethnicity in substance abuse, 2021, p. 1-19

Aims: To examine psychometric properties of the Daily Drinking Questionnaire (DDQ) in a Mediterranean “wet” drinking culture. Methods: Three studies were conducted using random samples drawn from a representative sample of Italian young adults (N¼5,955; females ¼ 62%; mean age ¼ 27): Study 1 explored the factorial structure of weekly alcohol consumption; in Study 2 multi-group...

Université de Fribourg

Short-term cardiovascular responses to ingestion of mineral water in healthy non-obese adults: Impact of mineral components

Monnard, Cathriona Rosemary ; Montani, Jean-Pierre ; Grasser, Erik Konrad

In: Journal of Functional Foods, 2020, vol. 71, p. 104017

Background: The role of mineral components in the hemodynamic response to water drinking is still elusive.Methods: We conducted a randomized crossover study in 16 non-obese, healthy subjects (8 women) to investigate cardiovascular responses to water drinks differing in the mineral content. Continuous measurements included beat- to-beat blood pressure, electrocardiography derived RR-intervals,...

Université de Fribourg

Dose-dependent heart rate responses to drinking water: a randomized crossover study in young, non-obese males

Grasser, Erik Konrad

In: Clinical Autonomic Research, 2020, p. -

The aim of the study was to explore a potential dose effect of water on heart rate responses and markers of vagal tone modulation.Methods: This was a randomized crossover study involving eight men whose heart rate and heart rate variability parameters were continuously measured following ingestion of different volumes of still mineral water (200, 400, 600, and 800 mL).Results: A significant...

Université de Fribourg

Differential expression of CD31 and von Willebrand factor on endothelial cells in different regions of the human brain: potential implications for cerebral malaria pathogenesis

Mbagwu, Smart Ikechukwu ; Filgueira, Luis

In: Brain Sciences, 2020, vol. 10, no. 1, p. 31

Cerebral microvascular endothelial cells (CMVECs) line the vascular system of the brain and are the chief cells in the formation and function of the blood brain barrier (BBB). These cells are heterogeneous along the cerebral vasculature and any dysfunctional state in these cells can result in a local loss of function of the BBB in any region of the brain. There is currently no report on the...

Université de Fribourg

Cardiovascular responses to a glucose drink in young male individuals with overweight/obesity and mild alterations in glucose metabolism, but without impaired glucose tolerance

Monnard, Cathriona R. ; Grasser, Erik Konrad

In: European Journal of Nutrition, 2019, p. -

Little is known about whether mild aberrations in glucose metabolism, which are seen in overweight/obese subjects (OW/OB) without impaired glucose tolerance, affect regulator control elements for blood pressure homeostasis. Methods Hence, we measured in age-matched male subjects with normal weight (n = 16; BMI = 22.4 kg m−2) and OW/OB (n = 11; BMI = 28.6 kg m−2) continuous...