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Università della Svizzera italiana

Epithelial-mesenchymal transition in cancer metastasis through the lymphatic syste

Karlsson, Mikael C. ; Gonzalez, Santiago F. ; Welin, Josefin ; Fuxe, Jonas

In: Molecular oncology, 2017, vol. 11, p. 781–791

It was already in the 18th century when the French surgeon LeDran first noted that breast cancer patients with spread of tumor cells to their axillary lymph nodes had a drastically worse prognosis than patients without spread (LeDran et al., ). Since then, metastatic spread of cancer cells to regional lymph nodes has been established as the most important prognostic factor in many types of...

Università della Svizzera italiana

Epigenetics of T lymphocytes in health and disease

Leoni, Cristina ; Vincenzetti, Lucia ; Emming, Stefan ; Monticelli, Silvia

In: Swiss Medical weekly, 2015, vol. 145, p. w14191

The risk of developing autoimmune diseases depends on both genetic and environmental factors, with epigenetic mechanisms of regulation potentially translating environmental cues into stable modifications in gene expression. Such stable memory of a functional state has been deciphered into a number of molecular mechanisms that collectively define the epigenetic status of a cell. In recent years,...

Université de Fribourg

Attitude Transference Among Adolescents : The Relationship Between Injunctive Classroom Norms and Individual Antisocial Attitudes

Hofmann, Verena ; Müller, Christoph M.

In: Journal of Cognitive Education and Psychology, 2016, vol. 15, p. 206-224

Cognition plays a major role in the development of antisocial behavior. The aim of this study was to extend the current state of research regarding the mechanisms of negative peer influence in adolescence by testing whether aggregated classroom attitudes (injunctive norms) predict individual attitudes towards antisocial behavior and vice versa. For that purpose, attitudes towards a broad range of...

Consortium of Swiss Academic Libraries

What's new in status epilepticus?

Rossetti, Andrea ; Bleck, Thomas

In: Intensive Care Medicine, 2014, vol. 40, no. 9, p. 1359-1362