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Induction of myocardial infarction in adult zebrafish using cryoinjury

Chablais, Fabian ; Jaźwińska, Anna

In: Journal of Visual Experiments, 2012, vol. 62, p. e3666

The mammalian heart is incapable of significant regeneration following an acute injury such as myocardial infarction. By contrast, urodele amphibians and teleost fish retain a remarkable capacity for cardiac regeneration with little or no scarring throughout life. It is not known why only some non-mammalian vertebrates can recreate a complete organ from remnant tissues. To understand the...