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Protein phosphatases and their potential implications in neuroprotective processes

Gee, C. ; Mansuy, I.

In: Cellular and Molecular Life Sciences CMLS, 2005, vol. 62, no. 10, p. 1120-1130

Université de Fribourg

The role of parvalbumin and calbindin D28k in experimental scrapie

Voigtländer, T. ; Unterberger, U. ; Guentchev, M. ; Schwaller, Beat ; Celio, Marco R. ; Meyer, M. ; Budka, H.

In: Neuropathology and Applied Neurobiology, 2008, vol. 34, no. 4, p. 435 - 445

Aims: Prion diseases are generally characterized by pronounced neuronal loss. In particular, a subpopulation of inhibitory neurones, characterized by the expression of the calcium-binding protein parvalbumin (PV), is selectively destroyed early in the course of human and experimental prion diseases. By contrast, nerve cells expressing calbindin D28k (CB), another calcium-binding protein, as well...