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    Université de Fribourg

    Molecular surgery concept from bench to bedside: a focus on TRPV1+ pain-sensing neurons

    Pecze, László ; Viskolcz, Béla ; Oláh, Zoltán

    In: Frontiers in Physiology, 2017, vol. 8, p. -

    “Molecular neurosurgery” is emerging as a new medical concept, and is the combination of two partners: (i) a molecular neurosurgery agent, and (ii) the cognate receptor whose activation results in the selective elimination of a specific subset of neurons in which this receptor is endogenously expressed. In general, a molecular surgery agent is a selective and potent ligand, and the target...