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Document type

Collection spécifique

Lingua

Université de Fribourg

Metabotropic glutamate receptor 5 in bulimia nervosa

Mihov, Yoan ; Treyer, Valerie ; Akkus, Funda ; Toman, Erika ; Milos, Gabriella ; Ametamey, Simon M. ; Johayem, Anass ; Hasler, Gregor

In: Scientific Reports, 2020, vol. 10, no. 1, p. 6374

Bulimia nervosa (BN) shares central features with substance-related and addictive disorders. The metabotropic glutamate receptor subtype 5 (mGlu5) plays an important role in addiction. Based on similarities between binge eating and substance-related and addictive disorders, we investigated mGlu5 in vivo in 15 female subjects with BN and 15 matched controls. We measured mGlu5 distribution...