Université de Fribourg

Orthostatic intolerance in older persons: etiology and countermeasures

Goswami, Nandu ; Blaber, Andrew P. ; Hinghofer-Szalkay, Helmut ; Montani, Jean-Pierre

In: Frontiers in Physiology, 2017, vol. 8, p. -

Orthostatic challenge produced by upright posture may lead to syncope if the cardiovascular system is unable to maintain adequate brain perfusion. This review outlines orthostatic intolerance related to the aging process, long-term bedrest immobilization, drugs, and disease. Aging-associated illness or injury due to falls often leads to hospitalization. Given that older patients spend up to...

Université de Fribourg

Time course of cardiovascular responses induced by mental and orthostatic challenges

Lackner, Helmut Karl ; Goswami, Nandu ; Papousek, Ilona ; Roessler, Andreas ; Grasser, Erik Konrad ; Montani, Jean-Pierre ; Jezova, Daniela ; Hinghofer-Szalkay, Helmut

In: International Journal of Psychophysiology, 2010, vol. 75, no. 1, p. 48-53

Cardiovascular responses to single stressors diminish over time. Interaction of different stressors influencing hemodynamic variables, indicative of stress-induced reactivity and physiological responses are, however, poorly understood. We investigated time course of mental (using mental arithmetic, MA) and orthostatic (using head up tilt, HUT) challenges induced responses in 16 males. Three...

Université de Fribourg

Rate of cardiovascular recovery to combined or separate orthostatic and mental challenges

Goswami, Nandu ; Lackner, Helmut Karl ; Papousek, Ilona ; Jezova, Daniela ; Hinghofer-Szalkay, Helmut ; Montani, Jean-Pierre

In: International Journal of Psychophysiology, 2010, vol. 75, no. 1, p. 54-62

Post stress neurovascular responses induced by physical and mental stress are poorly understood. We investigated the time course of cardiovascular and autonomic recovery, induced by orthostatic and mental challenge, using passive head up tilt (HUT) and mental arithmetic (MA), respectively, when applied singly (MA, HUT) or in combination (MA + HUT). Fifteen healthy males participated in three...