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Université de Fribourg

Radiation exposure of the operator during coronary interventions (from the RADIO Study)

Kallinikou, Zacharenia ; Puricel, Serban G. ; Ryckx, Nick ; Togni, Mario ; Baeriswyl, Gerard ; Stauffer, Jean-Christophe ; Cook, Stéphane ; Verdun, Francis R. ; Goy, Jean-Jacques

In: The American Journal of Cardiology, 2016, vol. 118, no. 2, p. 188–194

We sought to compare operator radiation exposure during procedures using right femoral access (RFA), right radial access (RRA), and left radial access (LRA) during coronary angiography (CA) and percutaneous coronary intervention (PCI). Because of an increased incidence of long-term malignancy in interventional cardiologists, operator radiation exposure is of rising concern. This prospective...

Université de Fribourg

Heart rate never lies: interventional cardiologist and Braude’s quote revised

Cook, Stéphane ; Stauffer, Jean-Christophe ; Goy, Jean-Jacques ; Graf, Denis ; Puricel, Serban ; Frobert, Aurélien ; Muller, Olivier ; Togni, Mario ; Arroyo, Diego

In: Open Heart, 2016, vol. 3, no. 1, p. e000373

Background Interventional cardiologists may be immune to stress, allowing them to perform complex percutaneous interventions under pressure.Objectives To assess heart rate (HR) variations as a surrogate marker of stress of interventional cardiologists during percutaneous cardiac procedures and in every-day life.Design This is a single-centre...

Université de Fribourg

Vascular response to everolimus- and biolimus-eluting coronary stents versus everolimus-eluting bioresorbable scaffolds – an optical coherence tomography substudy of the EVERBIO II trial

Kallinikou, Zacharenia ; Arroyo, Diego ; Togni, Mario ; Lehmann, Sonja ; Corpataux, Noé ; Cook, Malica ; Müller, Olivier ; Baeriswyl, Gérard ; Stauffer, Jean-Christophe ; Goy, Jean-Jacques ; Puricel, Serban ; Cook, Stéphane

In: Swiss Medical Weekly, 2016, p. -

QUESTIONS UNDER STUDY: Head-to-head optical coherence tomography (OCT) data comparing metallic stents with bioresorbable vascular scaffolds (BVS) are lacking. This study assessed vascular healing at 9-month follow-up after implantation of everolimus- and biolimus-eluting stents (EES BES) and everolimus-eluting BVS.METHODS: OCT was performed in 74 patients enrolled in the EVERBIO II (NCT01711931)...

Université de Fribourg

Comparison of everolimus-eluting and biolimus-eluting coronary stents with everolimus-eluting bioresorbable scaffold: study protocol of the randomized controlled EVERBIO II trial

Arroyo, Diego ; Togni, Mario ; Puricel, Serban ; Gerard, Baeriswyl ; Sonja, Lehmann ; Corpataux, Noé ; Villeneuve, Hélène ; Boute, Estelle ; Stauffer, Jean-Christophe ; Goy, Jean-Jacques ; Cook, Stéphane

In: Trials, 2014, vol. 15, no. 1, p. 9

Background: Second-generation everolimus-eluting stents (EES) and third generation biolimus-eluting stents (BES) have been shown to be superior to first-generation paclitaxel-eluting stents (PES) and second-generation sirolimus-eluting stents (SES). However, neointimal proliferation and very late stent thrombosis is still an unresolved issue of drug-eluting stent (DES) implantation overall. The...

Université de Fribourg

A randomized comparison of platelet reactivity in patients after treatment with various commercial clopidogrel preparations: The CLO-CLO trial = Étude randomisée comparant la réactivité plaquettaire des patients traités par diverses préparations commerciales de clopidogrel. Étude CLO-CLO

Oberhänsli, Markus ; Lehner, Cédric ; Puricel, Serban ; Lehmann, Sonja ; Togni, Mario ; Stauffer, Jean-Christophe ; Baeriswyl, Gérard ; Goy, Jean-Jacques ; Cook, Stéphane

In: Archives of Cardiovascular Diseases, 2012, vol. 105, no. 11, p. 587–592

BackgroundThe salt linked to the clopidogrel molecule in generic preparations is suspected to affect its clinical efficacy. There is a lack of information about inhibition of platelet reactivity by generic preparations.AimsTo compare the effect of original clopidogrel (clopidogrel bisulphate [Plavix®]), generic clopidogrel preparations (clopidogrel hydrochloride...

Université de Fribourg

Comparison of Titanium-Nitride-Oxide–Coated stents with Zotarolimus-Eluting stents for coronary revascularization: a randomized controlled trial

Pilgrim, Thomas ; Räber, Lorenz ; Limacher, Andreas ; Löffel, Lukas ; Wenaweser, Peter ; Cook, Stéphane ; Stauffer, Jean-Christophe ; Togni, Mario ; Vogel, Rolf ; Garachemani, Ali ; Moschovitis, Aris ; Khattab, Ahmed A. ; Seiler, Christian ; Meier, Bernhard ; Jüni, Peter ; Windecker, Stephan

In: Journal of the American College of Cardiology: Cardiovascular Interventions, 2011, vol. 4, no. 6, p. 672-682

Objectives: This study sought to compare the efficacy of passive stent coating with titanium-nitride-oxide (TiNO) with drug-eluting stents releasing zotarolimus (ZES) (Endeavor, Medtronic, Minneapolis, Minnesota).Background: Stent coating with TiNO has been shown to reduce restenosis compared with bare-metal stents in experimental and clinical studies.Methods: In an assessor-blind noninferiority...