In: American Journal of Physiology-Endocrinology and Metabolism, 2019, vol. 317, no. 4, p. E699–E709
The recovery of body weight after substantial weight loss or growth retardation is often characterized by a disproportionately higher rate of fat mass vs. lean mass recovery, with this phenomenon of “preferential catch-up fat” being contributed by energy conservation (thrifty) metabolism. To test the hypothesis that a low core body temperature (Tc) constitutes a thrifty metabolic trait...
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In: Nutrients, 2019, vol. 11, no. 7, p. 1599
Implementation of efficacious dietary interventions to regulate energy balance requires understanding of the determinants of individual response. To date, information regarding individual variability in response to elevated meal protein content is lacking. This study investigates whether sex and/or oral contraceptive pill (OCP) use play a role in the response to elevated meal protein in 21...
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In: Frontiers in Endocrinology, 2019, vol. 10, p. -
Objective: The recovery of body composition after weight loss is characterized by an accelerated rate of fat recovery (preferential catch-up fat) resulting partly from an adaptive suppression of thermogenesis. Although the skeletal muscle has been implicated as an effector site for such thrifty (energy conservation) metabolism driving catch-up fat, the underlying mechanisms remain to be...
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In: European Journal of Clinical Nutrition, 2018, vol. 72, no. 5, p. 657–664
Collateral fattening refers to the process whereby excess fat is deposited as a result of the body’s attempt to counter a deficit in lean mass through overeating. Its demonstration and significance to weight regulation and obesity can be traced to work on energy budget strategies in growing mammals and birds, and to men recovering from experimental starvation. The cardinal features of...
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In: Frontiers in Physiology, 2017, vol. 8, p. -
There is increasing recognition that low-intensity physical activities of daily life play an important role in achieving energy balance and that their societal erosion through substitution with sedentary (mostly sitting) behaviours, whether occupational or for leisure, impact importantly on the obesity epidemic. This has generated considerable interest for better monitoring, characterizing...
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In: Obesity, 2017, vol. 25, no. 9, p. 1482–1485
Objective: There is much interest in the role of dietary protein for weight control. However, there remains a need to characterize individual determinants of the thermogenic effects of protein. This study aimed to investigate the influence of menstrual cycle phase and the combined, monophasic oral contraceptive pill on the thermogenic response to a standardized high-protein (HP) versus...
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In: Frontiers in Endocrinology, 2017, vol. 8, p. -
Background: There is increasing interest in the use of pill-sized ingestible capsule telemetric sensors for assessing core body temperature (Tc) as a potential indicator of variability in metabolic efficiency and thrifty metabolic traits. The aim of this study was to investigate the feasibility and accuracy of measuring Tc using the CorTemp® system.Methods: Tc was measured over an average of 20...
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In: Journal of Nutritional Science, 2013, vol. 2, p. -
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In: European Journal of Applied Physiology, 2017, vol. 117, no. 4, p. 795–807
Due to sedentarity-associated disease risks, there is much interest in methods to increase low-intensity physical activity. In this context, it is widely assumed that altering posture allocation can modify energy expenditure (EE) to impact body-weight regulation and health. However, we have recently shown the existence of two distinct phenotypes pertaining to the energy cost of...
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In: Physiological Reports, 2017, vol. 5, no. 9, p. e13233
Standardized approaches to assess human energy expenditure (EE) are well defined at rest and at moderate to high‐intensity exercise, but not at light intensity physical activities energetically comparable with those of daily life (i.e., 1.5–4 times the resting EE, i.e., 1.5–4 METs). Our aim was to validate a graded exercise test for assessing the energy cost of low‐intensity dynamic...
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