Université de Fribourg

Age-related differences in cortical and subcortical activities during observation and motor imagery of dynamic postural tasks: an FMRI study

Mouthon, Audrey ; Ruffieux, Jan ; Mouthon, Michael ; Hoogewoud, Henri-Marcel ; Annoni, Jean-Marie ; Taube, Wolfgang

In: Neural Plasticity, 2018, p. -

Age-related changes in brain activation other than in the primary motor cortex are not well known with respect to dynamic balance control. Therefore, the current study aimed to explore age-related differences in the control of static and dynamic postural tasks using fMRI during mental simulation of balance tasks. For this purpose, 16 elderly (72 ± 5 years) and 16 young adults...

Université de Fribourg

Brain activity during observation and motor imagery of different balance tasks: An fMRI study

Taube, Wolfgang ; Mouthon, Michael ; Leukel, Christian ; Hoogewoud, Henri-Marcel ; Annoni, Jean-Marie ; Keller, Martin

In: Cortex, 2015, vol. 64, p. 102–114

After immobilization, patients show impaired postural control and increased risk of falling. Therefore, loss of balance control should already be counteracted during immobilization. Previously, studies have demonstrated that both motor imagery (MI) and action observation (AO) can improve motor performance. The current study elaborated how the brain is activated during imagination and observation...

Université de Fribourg

Refined methodology for implantation of a head fixation device and chronic recording chambers in non-human primates

Lanz, Florian ; Lanz, X. ; Scherly, A. ; Moret, Véronique ; Gaillard, A. ; Gruner, P. ; Hoogewoud, Henri-Marcel ; Belhaj-Saif, Abderraouf ; Loquet, Gérard ; Rouiller, Eric M.

In: Journal of Neuroscience Methods, 2013, vol. 219, no. 2, p. 262–270

The present study was aimed at developing a new strategy to design and anchor custom-fitted implants, consisting of a head fixation device and a chronic recording chamber, on the skull of adult macaque monkeys. This was done without the use of dental resin or orthopedic cement, as these modes of fixation exert a detrimental effect on the bone. The implants were made of titanium or tekapeek and...

Université de Fribourg

Follow-up of cortical activity and structure after lesion with laser speckle imaging and magnetic resonance imaging in nonhuman primates

Peuser, Jörn ; Belhaj-Saif, Abderraouf ; Hamadjida, Adjia ; Schmidlin, Eric ; Gindrat, Anne-Dominique ; Völker, Andreas Charles ; Zakharov, Pavel ; Hoogewoud, Henri-Marcel ; Rouiller, Eric M. ; Scheffold, Frank

In: Journal of Biomedical Optics, 2011, vol. 16, no. 09, p. 096011

The nonhuman primate model is suitable to study mechanisms of functional recovery following lesion of the cerebral cortex (motor cortex), on which therapeutic strategies can be tested. To interpret behavioral data (time course and extent of functional recovery), it is crucial to monitor the properties of the experimental cortical lesion, induced by infusion of the excitotoxin ibotenic acid. In...