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Brain networks modulated by subthalamic nucleus deep brain stimulation

Accolla, Ettore A. ; Ruiz, Maria Herrojo ; Horn, Andreas ; Schneider, Gerd-Helge ; Schmitz-Hübsch, Tanja ; Draganski, Bogdan ; Kühn, Andrea A.

In: Brain, 2016, vol. 139, no. 9, p. 2503–2515

Deep brain stimulation of the subthalamic nucleus is an established treatment for the motor symptoms of Parkinson’s disease. Given the frequent occurrence of stimulation- induced affective and cognitive adverse effects, a better understanding about the role of the subthalamic nucleus in non-motor functions is needed. The main goal of this study is to characterize anatomical circuits...