In: Nature Nanotechnology, 2010, vol. 5, p. 423 - 428
The aggregation of proteins is central to many aspects of daily life, including food processing, blood coagulation, eye cataract formation disease and prion-related neurodegenerative infections. However, the physical mechanisms responsible for amyloidosis—the irreversible fibril formation of various proteins that is linked to disorders such as Alzheimer's, Creutzfeldt–Jakob and Huntington's...
|
In: Langmuir, 2010, vol. 26, no. 13, p. 10401–10405
We investigate the effects of variable linear charge density and Debye length on the mesoscopic properties of β-lactoglobulin fibers in water, by changing the pH and ionic strength, respectively. We determine the isotropic−nematic (I−N) transition by cross-polarized microscopy and quantify by atomic force microscopy the increasing tendency of the fibers to aggregate upon raising ionic...
|