In: Acta Neuropathologica, 2012, vol. 123, no. 6, p. 841-852
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In: Strahlentherapie und Onkologie, 2006, vol. 182, no. 8, p. 450-457
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In: Clinical Cancer Research, 2012, vol. 18, no. 16, p. 4365-4374
Purpose: Local breast cancer relapse after breast-saving surgery and radiotherapy is associated with increased risk of distant metastasis formation. The mechanisms involved remain largely elusive. We used the well-characterized 4T1 syngeneic, orthotopic breast cancer model to identify novel mechanisms of post-radiation metastasis. Experimental Design: 4T1 cells were injected in 20 Gy...
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In: PLoS ONE, 2010, vol. 5, no. 6, p. e11084
Background: Radiotherapy is widely used to treat cancer. While rapidly dividing cancer cells are naturally considered the main target of radiotherapy, emerging evidence indicates that radiotherapy also affects endothelial cell functions, and possibly also their angiogenic capacity. In spite of its clinical relevance, such putative anti-angiogenic effect of radiotherapy has not been thoroughly...
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