Université de Fribourg

Efferent connections of the parvalbumin-positive (PV1) nucleus in the lateral hypothalamus of rodents

Celio, Marco R. ; Babalian, Alexandre ; Ha, Quan Hue ; Eichenberger, Simone ; Clément, Laurence ; Marti, Christiane ; Saper, Clifford B.

In: Journal of Comparative Neurology, 2013, vol. 521, no. 14, p. 3133–3153

A solitary cluster of parvalbumin-positive neurons – the PV1 nucleus – has been observed in the lateral hypothalamus of rodents. In the present study, we mapped the efferent connections of the PV1 nucleus using nonspecific antero- and retrograde tracers in rats, and chemoselective, Cre-dependent viral constructs in parvalbumin-Cre mice. In both species, the PV1 nucleus was found to project...

Université de Fribourg

The lateral hypothalamic parvalbumin-immunoreactive (PV1) nucleus in rodents

Mészár, Zoltán ; Girard, Franck ; Saper, Clifford B. ; Celio, Marco R.

In: The Journal of Comparative Neurology, 2011, p. -

In the lateral hypothalamus, groups of functionally related cells tend to be widely scattered rather than confined to discrete, anatomically distinct units. However, using parvalbumin (PV)-specific antibodies, a solitary, compact cord of PV-immunoreactive cells (the PV1-nucleus) has been identified in the ventrolateral tuberal hypothalamus in various species. Here we describe the topography, the...