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Université de Fribourg

Vibronic spectra of the p-benzoquinone radical anion and cation: a matrix isolation and computational study

Piech, Krzysztof ; Bally, Thomas ; Ichino, Takatoshi ; Stanton, John

In: Physical Chemistry Chemical Physics, 2013, vol. 16, no. 5, p. 2011–2019

The electronic and vibrational absorption spectra of the radical anion and cation of p-benzoquinone (PBQ) in an Ar matrix between 500 and 40 000 cm⁻¹ are presented and discussed in detail. Of particular interest is the radical cation, which shows very unusual spectroscopic features that can be understood in terms of vibronic coupling between the ground and a very low-lying excited...

Université de Fribourg

Experimental evidence on the mechanism of dissociative electron attachment to formic acid

Janečková, Radmila ; Kubala, Dušan ; May, Olivier ; Fedor, Juraj ; Allan, Michael

In: Physical Review Letters, 2013, vol. 111, no. 21, p. 213201

Two mechanisms for dissociative electron attachment in HCOOH, the formation of HCOO−+H, were proposed in the literature: (i) via a direct electron attachment into a σ∗ resonance, augmented by dipole binding of the incident electron [G. A. Gallup et al., Phys. Rev. A 79, 042701 (2009)], and (ii) with the 1.8 eV π∗ resonance as a doorway state, linked to the products by...

Université de Fribourg

Increased seed survival and seedling emergence in a polyploid plant invader

Hahn, Min A. ; Lanz, Tabea ; Fasel, Dominique ; Müller-Schärer, Heinz

In: American Journal of Botany, 2013, vol. 100, no. 8, p. 1555–1561

Premise of the study: Because seeds have essential functions in the life cycle of plants, even subtle changes in their characteristics may have important demographic consequences. In this study, we examined whether potential changes in seed characteristics as a result of polyploidy or postintroduction evolution may have contributed to the invasion of Centaurea stoebe (Asteraceae). This plant...

Université de Fribourg

Sachsen zwischen Landesbewusstein und Nationsbildung 1866-1871

Weichlein, Siegfried

In: Sachsen im Kaiserreich - Politik, Wirtschaft und Gesellschaft im Umbruch, 1997, p. 241-270

Université de Fribourg

"Non romanzeggia ma narra fatti". L'ultimo "racconto vero" del padre Bresciani

Martini, Alessandro

In: Marco Praloran 1955-2011 - Studi offerti dai colleghi delle università svizzere, 2013, p. 193-208

Université de Fribourg

Cross-limb interference during motor learning

Lauber, Benedikt ; Lundbye-Jensen, Jesper ; Keller, Martin ; Gollhofer, Albert ; Taube, Wolfgang ; Leukel, Christian

In: PLoS ONE, 2013, vol. 8, no. 12, p. e81038

It is well known that following skill learning, improvements in motor performance may transfer to the untrained contralateral limb. It is also well known that retention of a newly learned task A can be degraded when learning a competing task B that takes place directly after learning A. Here we investigate if this interference effect can also be observed in the limb contralateral to the trained...

Université de Fribourg

Binary cell fate decisions and fate transformation in the Drosophila larval eye

Mishra, Abhishek Kumar ; Tsachaki, Maria ; Rister, Jens ; Ng, June ; Celik, Arzu ; Sprecher, Simon G.

In: PLoS Genet, 2013, vol. 9, no. 12, p. e1004027

Controlling cellular diversity requires a complex interplay of transcription factors. Using the Drosophila larval eye as genetic model we identify distinct mechanisms of how binary cell fate decisions are made, how sensory receptor gene expression is regulated and how cell fate identity is switched during metamorphosis. We show that the transcription factor Senseless fulfills three temporally...

Université de Fribourg

Expression of a microbial serine proteinase inhibitor gene enhances the tobacco defense against oomycete pathogens

Silva, Yussuan ; Portieles, Roxana ; Pujol, Merardo ; Terauchi, Ryohei ; Matsumura, Hideo ; Serrano, Mario ; Borrás-Hidalgo, Orlando

In: Physiological and Molecular Plant Pathology, 2013, vol. 84, p. 99–106

In order to identify Nicotiana megalosiphon genes for novel inhibitors of microbial serine proteinase involved in resistance to the oomycete Phytophthora parasitica var. nicotianae, SuperSAGE technology combined with next-generation sequencing were used to generate libraries in order to identify transcripts that are differentially up-regulated. We identified a N. megalosiphon inhibitor of...

Université de Fribourg

The natural diyne-furan fatty acid EV-086 is an inhibitor of fungal delta-9 fatty acid desaturation with efficacy in a model of skin dermatophytosis

Knechtle, Philipp ; Diefenbacher, Melanie ; Greve, Katrine B. V. ; Brianza, Federico ; Folly, Christophe ; Heider, Harald ; Lone, Museer A. ; Long, Lisa ; Meyer, Jean-Philippe ; Roussel, Patrick ; Ghannoum, Mahmoud A. ; Schneiter, Roger ; Sorensen, Alexandra S.

In: Antimicrobial Agents and Chemotherapy, 2013, vol. 58, no. 1, p. 455–466

Human fungal infections represent a therapeutic challenge. Although effective strategies for treatment are available, resistance is spreading, and many therapies have unacceptable side effects. A clear need for novel antifungal targets and molecules is thus emerging. Here, we present the identification and characterization of the plant-derived diyne-furan fatty acid EV-086 as a novel antifungal...