In: Trends in Plant Science, 2006, vol. 11, no. 7, p. 320-322
FiRe is a user-friendly Excel® macro designed to survey microarray data rapidly. This software interactively assembles data from different experiments and produces lists of candidate genes according to patterns of gene expression. Furthermore, macros bundled with FiRe can compare lists of genes, merge information from different spreadsheets, link candidates to information available from...
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In: Inorganica Chimica Acta, 2006, vol. 359, no. 12, p. 3865-3870
The hybrid density functional theory is applied to calculate the electron paramagnetic resonance parameters, i.e, the g- and A-tensors of some planar Cobalt(II) complexes with a C2v symmetry. Calculations were done for four systems: Co(acacen), Co(tacacen), Co(seacacen) and...
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Thèse de doctorat : Université de Fribourg, 2006.
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Thèse de doctorat : Université de Fribourg, 2006.
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In: Journal of the American Society of Nephrology, 2006, vol. 17, p. 1264-1274
The activity of the epithelial sodium (Na⁺) channel (ENaC) in the aldosterone-sensitive distal nephron (ASDN) needs to be tightly regulated to match urinary Na⁺ excretion with dietary Na⁺ intake. The ubiquitin-protein ligase Nedd4-2, which in vitro interacts with ENaC subunits and reduces ENaC cell surface abundance and activity by ubiquitylation of the channel, may participate in...
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In: Nature Medicine
In rodents, after spinal lesion, neutralizing the neurite growth inhibitor Nogo-A promotes axonal sprouting and functional recovery. To evaluate this treatment in primates, 12 monkeys were subjected to cervical lesion. Recovery of manual dexterity and sprouting of corticospinal axons were enhanced in monkeys treated with Nogo-A– specific antibody as compared to monkeys treated with control...
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In: Learning & Memory, 2006, vol. 13, p. 84-96
This experiment assesses spatial and nonspatial relational memory in freely moving 9-mo-old and adult (11-13-yr-old) macaque monkeys (Macaca mulatta). We tested the use of proximal landmarks, two different objects placed at the center of an open-field arena, as conditional cues allowing monkeys to predict the location of food rewards hidden in one of two sets of three distinct locations....
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In: The Journal of Neuroscience, 2006, vol. 26(17), p. 4546-4558
The role of the hippocampus in spatial learning and memory has been extensively studied in rodents. Comparable studies in nonhuman primates, however, are few, and findings are often contradictory. This may be attributable to the failure to distinguish between allocentric and egocentric spatial representations in experimental designs. For this experiment, six adult monkeys received bilateral...
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In: Endocrinology, 2006, vol. 147(1), p. 31-38
The mechanisms by which CRH and related peptides (i.e. the CRH/urocortin system) exert their control over thermogenesis and weight regulation have until now focused only upon their effects on brain centers controlling sympathetic outflow. Using a method that involves repeated oxygen uptake determinations in intact mouse skeletal muscle, we report here that CRH can act directly on skeletal...
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Thèse de doctorat : Université de Fribourg, 2005.
Cette étude est réalisée dans le cadre de la recherche sur les processus psychothérapeutiques et leurs effets, en fonction de différentes formes d’interventions approfondissantes. De plus, elle tient compte des caractéristiques préalables du client susceptibles de modérer l’impact cognitif et émotionnel de ces interventions. Dans cette étude expérimentale et analogue, on applique...
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