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Université de Fribourg

The art of fin regeneration in zebrafish

Pfefferli, Catherine ; Jaźwińska, Anna

In: Regeneration, 2015, p. -

The zebrafish fin provides a valuable model to study the epimorphic type of regeneration, by which the amputated part of the appendage is nearly perfectly replaced. To accomplish fin regeneration, two reciprocally interacting domains need to be established at the injury site, namely, a wound epithelium and a blastema. The wound epithelium provides a supporting niche for the blastema, which...

Université de Neuchâtel

Entre motivations et arbitrages: le choix résidentiel au sein des couples : habiter au centre-ville, l'exemple du Parc de la Suze à Bienne

Gurtner, Maureen ; Rérat, Patrick (Dir.)

Mémoire de master : Université de Neuchâtel, 2013.

Depuis les années 2000, la réurbanisation, en réponse à la tendance de l’étalement urbain, est observée. En effet, les villes sont, à nouveau, dans une phase de croissance du nombre de leurs habitants qui se traduit par des opérations de régénération de friches urbaines. Il est ainsi important de comprendre les raisons qui incitent les personnes à rejoindre les centres-villes. Notre...

Université de Fribourg

Invasion of lesion territory by regenerating fibers after spinal cord injury in adult macaque monkeys

Beaud, Marie-Laure ; Rouiller, Eric M. ; Bloch, Jocelyne ; Mir, Anis ; Schwab, M.E. ; Wannier, Thierry ; Schmidlin, Eric

In: Neuroscience, 2012, vol. 27, p. 271–282

In adult macaque monkeys subjected to an incomplete spinal cord injury (SCI), corticospinal (CS) fibers are rarely observed to grow in the lesion territory. This situation is little affected by the application of an anti-Nogo-A antibody which otherwise fosters the growth of CS fibers rostrally and caudally to the lesion. However, when using the Sternberger monoclonal-incorporated antibody 32...

Université de Fribourg

Induction of myocardial infarction in adult zebrafish using cryoinjury

Chablais, Fabian ; Jaźwińska, Anna

In: Journal of Visual Experiments, 2012, vol. 62, p. e3666

The mammalian heart is incapable of significant regeneration following an acute injury such as myocardial infarction. By contrast, urodele amphibians and teleost fish retain a remarkable capacity for cardiac regeneration with little or no scarring throughout life. It is not known why only some non-mammalian vertebrates can recreate a complete organ from remnant tissues. To understand the...

Université de Fribourg

Upregulated expression of oncomodulin, the beta isoform of parvalbumin, in perikarya and axons in the diencephalon of parvalbumin knockout mice

Csillik, B. ; Schwaller, Beat ; Mihaly, A. ; Henzi, Thomas ; Losonczi, E. ; Knyihar-Csillik, E.

In: Neuroscience, 2010, vol. 165, no. 3, p. 749-757

The calcium-binding proteins parvalbumin, calbindin D-28k, calretinin and calcineurin are present in subsets of GABAergic gigantic calyciform presynaptic terminals of the reticular thalamic nucleus (RTN). Previously it was hypothesized that GABA and calcium-binding proteins including parvalbumin are not only colocalized in the same neuron subpopulation, but that GABA synthesis and parvalbumin...