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Lentiviral Vector-Mediated Gene Transfer and RNA Silencing Technology in Neuronal Dysfunctions

Dreyer, Jean-Luc

In: Molecular Biotechnology, 2011, vol. 47, no. 2, p. 169-187

Hairpin RNA: a secondary structure of primary importance

Svoboda, P. ; Cara, A.

In: Cellular and Molecular Life Sciences CMLS, 2006, vol. 63, no. 7-8, p. 901-908

Regulation of MiR-124, Let-7d, and MiR-181a in the accumbens affects the expression, extinction, and reinstatement of cocaine-induced conditioned place preference

Chandrasekar, Vijay ; Dreyer, Jean-Luc

In: Neuropsychopharmacology, 2011, vol. 36, p. 1149-1164

Molecular adaptations underlying drug seeking and relapse remain largely unknown. Studies highlight post-transcriptional modifications mediated by microRNAs (miRNAs) in addiction and other neurological disorders. We have previously shown that chronic cocaine suppresses miR-124 and let-7d and induces the expression of miR-181a in mesolimbic pathway. To further address the role and target gene...